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ATM gene

Known as: ataxia telangiectasia mutated (ATM) gene, ATAXIA-TELANGIECTASIA MUTATED GENE, TEL1 
This gene is involved in apoptosis, DNA repair and cell cycle regulation.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The multifunctional Mre11-Rad50-Nbs1 (MRN) protein complex recruits ATM/Tel1 checkpoint kinase and CtIP/Ctp1 homologous… Expand
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Highly Cited
2008
Highly Cited
2008
An essential feature of meiosis is interhomolog recombination whereby a significant fraction of the programmed meiotic double… Expand
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Highly Cited
2007
Highly Cited
2007
Understanding the role of DNA damage checkpoint kinases in the cellular response to genotoxic stress requires the knowledge of… Expand
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Highly Cited
2006
Highly Cited
2006
One of the earliest marks of a double-strand break (DSB) in eukaryotes is serine phosphorylation of the histone variant H2AX at… Expand
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Highly Cited
2005
Highly Cited
2005
ABSTRACT ATM has a central role in controlling the cellular responses to DNA damage. It and other phosphoinositide 3-kinase… Expand
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Highly Cited
2005
Highly Cited
2005
The yeast checkpoint kinases Mec1 and Rad53 are required for genomic stability in the presence of replicative stress. When… Expand
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Highly Cited
2001
Highly Cited
2001
We find budding yeast Rad9 in two distinct, large, and soluble complexes in cell extracts. The larger (> or =850 kDa) complex… Expand
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Highly Cited
1998
Highly Cited
1998
In the budding yeast, Saccharomyces cerevisiae, genes in close proximity to telomeres are subject to transcriptional silencing… Expand
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Highly Cited
1997
Highly Cited
1997
Yeast have many genes with homologs in humans. Has our understanding of these genes helped our understanding of human biology or… Expand
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Highly Cited
1996
Highly Cited
1996
Mutants of the Saccharomyces cerevisiae ataxia telangiectasia mutated (ATM) homolog MEC1/SAD3/ESR1 were identified that could… Expand
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