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Antigen Targeting
Antigen Targeting involves specific and high affinity non-covalent interaction (binding) of an antibody reagent through intermolecular physical…
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National Institutes of Health
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Related topics
Related topics
3 relations
Antigens
Immunity
MoAb Bombesin (ITC-D)
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Increasing vaccine potency through exosome antigen targeting.
Z. Hartman
,
Junping Wei
,
+10 authors
H. Lyerly
Vaccine
2011
Corpus ID: 45187687
While many tumor associated antigens (TAAs) have been identified in human cancers, efforts to develop efficient TAA "cancer…
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Highly Cited
2010
Highly Cited
2010
Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR.
E. Klechevsky
,
Anne-Laure Flamar
,
+11 authors
J. Banchereau
Blood
2010
Corpus ID: 2648511
We evaluated human CD8(+) T-cell responses generated by targeting antigens to dendritic cells (DCs) through various lectin…
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Highly Cited
2010
Highly Cited
2010
Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A
Olivier P. Joffre
,
D. Sancho
,
S. Zelenay
,
A. M. Keller
,
C. Reis e Sousa
European journal of immunology
2010
Corpus ID: 16741154
DC NK lectin group receptor‐1 (DNGR‐1, also known as CLEC9A) is a C‐type lectin receptor expressed by mouse CD8α+ DC and by their…
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Highly Cited
2008
Highly Cited
2008
Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin.
D. Sancho
,
D. Mourão-Sá
,
+5 authors
C. Reis e Sousa
The Journal of clinical investigation
2008
Corpus ID: 4946032
The mouse CD8alpha+ DC subset excels at cross-presentation of antigen, which can elicit robust CTL responses. A receptor allowing…
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Highly Cited
2007
Highly Cited
2007
Exploiting lymphatic transport and complement activation in nanoparticle vaccines
S. T. Reddy
,
A. J. V. D. Vlies
,
+6 authors
J. Hubbell
Nature Biotechnology
2007
Corpus ID: 17327939
Antigen targeting and adjuvancy schemes that respectively facilitate delivery of antigen to dendritic cells and elicit their…
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Highly Cited
2006
Highly Cited
2006
The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture.
P. Schnorrer
,
G. Behrens
,
+12 authors
J. Villadangos
Proceedings of the National Academy of Sciences…
2006
Corpus ID: 28640633
Mouse spleens contain three populations of conventional (CD11c(high)) dendritic cells (DCs) that play distinct functions. The CD8…
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Highly Cited
2006
Highly Cited
2006
Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses
S. Boscardin
,
J. C. Hafalla
,
+8 authors
M. Nussenzweig
The Journal of experimental medicine
2006
Corpus ID: 1752422
Resistance to several prevalent infectious diseases requires both cellular and humoral immune responses. T cell immunity is…
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Highly Cited
2005
Highly Cited
2005
Design of Soluble Recombinant T Cell Receptors for Antigen Targeting and T Cell Inhibition*
Bruno Laugel
,
J. Boulter
,
+9 authors
A. Sewell
Journal of Biological Chemistry
2005
Corpus ID: 38833344
The use of recombinant T cell receptors (TCRs) to target therapeutic interventions has been hindered by the naturally low…
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Highly Cited
2004
Highly Cited
2004
In Vivo Targeting of Antigens to Maturing Dendritic Cells via the DEC-205 Receptor Improves T Cell Vaccination
L. Bonifaz
,
D. Bonnyay
,
+7 authors
R. Steinman
The Journal of experimental medicine
2004
Corpus ID: 1833553
The prevention and treatment of prevalent infectious diseases and tumors should benefit from improvements in the induction of…
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Highly Cited
1999
Highly Cited
1999
Modulation of the humoral immune response by antibody-mediated antigen targeting to complement receptors and Fc receptors.
D. Baiu
,
J. Prechl
,
+5 authors
W. Hazenbos
Journal of immunology
1999
Corpus ID: 24875833
During an ongoing immune response, immune complexes, composed of Ag, complement factors, and Igs, are formed that can interact…
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