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Antigen Targeting

Antigen Targeting involves specific and high affinity non-covalent interaction (binding) of an antibody reagent through intermolecular physical… 
National Institutes of Health

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AntigensImmunityMoAb Bombesin (ITC-D)

Papers overview

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2016
2016
Intracellular chromobody delivery by mesoporous silica nanoparticles for antigen targeting and visualization in real time
Chromobodies have recently drawn great attention as bioimaging nanotools. They offer high antigen binding specificity and… 
Highly Cited
2012
Highly Cited
2012
Fcγ receptor antigen targeting potentiates cross-presentation by human blood and lymphoid tissue BDCA-3+ dendritic cells.
The reactivation of human cytomegalovirus (HCMV) poses a serious health threat to immune compromised individuals. As a treatment… 
Highly Cited
2011
Highly Cited
2011
Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses
The αE integrin chain CD103 identifies a subset of migratory dendritic cells (DCs) in the gut, lung, and skin. To gain further… 
Highly Cited
2010
Highly Cited
2010
Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR.
We evaluated human CD8(+) T-cell responses generated by targeting antigens to dendritic cells (DCs) through various lectin… 
Highly Cited
2010
Highly Cited
2010
Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A
DC NK lectin group receptor‐1 (DNGR‐1, also known as CLEC9A) is a C‐type lectin receptor expressed by mouse CD8α+ DC and by their… 
Review
2010
Review
2010
Targeting of antigens to skin dendritic cells: possibilities to enhance vaccine efficacy
Vaccinations in medicine are commonly administered through the skin. Therefore, the vaccine is immunologically processed by… 
Review
2005
Review
2005
Adjuvants and antibody production: dispelling the myths associated with Freund's complete and other adjuvants.
Adjuvants have been used for more than 70 yr to enhance the immune response of the host animal to an antigen. Among the… 
Highly Cited
2005
Highly Cited
2005
Design of Soluble Recombinant T Cell Receptors for Antigen Targeting and T Cell Inhibition*
The use of recombinant T cell receptors (TCRs) to target therapeutic interventions has been hindered by the naturally low… 
Highly Cited
1999
Highly Cited
1999
Modulation of the humoral immune response by antibody-mediated antigen targeting to complement receptors and Fc receptors.
During an ongoing immune response, immune complexes, composed of Ag, complement factors, and Igs, are formed that can interact… 
Highly Cited
1989
Highly Cited
1989
Efficiency of antigen presentation after antigen targeting to surface IgD, IgM, MHC, Fc gamma RII, and B220 molecules on murine splenic B cells.
Bispecific heteroconjugate antibodies can bind soluble protein Ag to APC and thereby enhance Ag presentation. We used such… 
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