Antigen Targeting

Antigen Targeting involves specific and high affinity non-covalent interaction (binding) of an antibody reagent through intermolecular physical… (More)
National Institutes of Health

Papers overview

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2011
2011
While many tumor associated antigens (TAAs) have been identified in human cancers, efforts to develop efficient TAA "cancer… (More)
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Highly Cited
2010
Highly Cited
2010
We evaluated human CD8(+) T-cell responses generated by targeting antigens to dendritic cells (DCs) through various lectin… (More)
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Review
2010
Review
2010
Vaccinations in medicine are commonly administered through the skin. Therefore, the vaccine is immunologically processed by… (More)
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Highly Cited
2010
Highly Cited
2010
DC NK lectin group receptor-1 (DNGR-1, also known as CLEC9A) is a C-type lectin receptor expressed by mouse CD8alpha+ DC and by… (More)
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Highly Cited
2008
Highly Cited
2008
The mouse CD8alpha+ DC subset excels at cross-presentation of antigen, which can elicit robust CTL responses. A receptor allowing… (More)
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Highly Cited
2007
Highly Cited
2007
Antigen targeting and adjuvancy schemes that respectively facilitate delivery of antigen to dendritic cells and elicit their… (More)
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Highly Cited
2006
Highly Cited
2006
Mouse spleens contain three populations of conventional (CD11c(high)) dendritic cells (DCs) that play distinct functions. The CD8… (More)
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Highly Cited
2006
Highly Cited
2006
Resistance to several prevalent infectious diseases requires both cellular and humoral immune responses. T cell immunity is… (More)
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2005
2005
The use of recombinant T cell receptors (TCRs) to target therapeutic interventions has been hindered by the naturally low… (More)
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Highly Cited
2004
Highly Cited
2004
The prevention and treatment of prevalent infectious diseases and tumors should benefit from improvements in the induction of… (More)
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