Anthracycline Antibiotics

Known as: anthracycline, Anthracyclines, Anthracycline Antineoplastic Antibiotic 
An antineoplastic antibiotic that is structurally similar to the benzoquinone ansamycin antibiotic geldanamycin. A geldanamycin analogue binds to… (More)
National Institutes of Health

Papers overview

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2004
2004
The increasing numbers of human immunodeficiency virus type 1 (HIV-1) strains that exhibit resistance to antiretroviral agents… (More)
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Highly Cited
2000
Highly Cited
2000
Doxorubicin (DOX) is a broad spectrum anthracycline antibiotic used to treat a variety of cancers. Redox activation of DOX to… (More)
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1996
1996
The DNA binding free energy of eight anthracycline antibiotics was determined as a function of NaCl concentration. Compounds were… (More)
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Review
1994
Review
1994
30 years ago an anthracycline antibiotic was shown to have antineoplastic activity. This led to the development of well over 1000… (More)
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1992
1992
Vomiting and nausea are the most distressing side-effects of cancer chemotherapy. With standard antiemetic regimens (e.g… (More)
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1992
1992
Helicases are essential to both DNA replication and transcription because they separate double-stranded DNA, preparing the single… (More)
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Highly Cited
1990
Highly Cited
1990
The anthracycline antibiotic doxorubicin produces a characteristic myopathy in cardiac muscle that limits its use in cancer… (More)
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1987
1987
The crystal structure of a daunomycin-d(CGTACG) complex has been solved by X-ray diffraction analysis and refined to a final R… (More)
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1984
1984
3'-Deamino-3'-(3-cyano-4-morpholinyl)doxorubicin is a new analogue that is 100 to 1000 times more potent than doxorubicin against… (More)
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Highly Cited
1978
Highly Cited
1978
Anthracycline derivatives may produce early or late cardiotoxic reactions in man. Early effects include: (a) pericarditis… (More)
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