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Daunorubicin

Known as: Daunorubicine, Daunomycin, DNM 
An anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Daunorubicin exhibits cytotoxic activity through… 
National Institutes of Health

Related topics

Related topics

49 relations

Narrower (34)

1-hydroxy-13-dihydrodaunomycin13-methyl-13-dihydrodaunorubicin14-quinaldinoyloxydaunorubicin4'-deoxydaunomycin

Broader (2)

Anthracycline AntibioticsAntibiotics, Antineoplastic
Congestive heart failureDAT regimenIn BloodLarson Regimen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1995
Highly Cited
1995
Effects of lipids on ATPase activity of purified Chinese hamster P-glycoprotein.
Chinese hamster P-glycoprotein ("multidrug-resistance protein") was purified and reconstituted in proteoliposomes by the… 
Highly Cited
1993
Highly Cited
1993
Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells.
Highly Cited
1990
Highly Cited
1990
Membrane vesicle formation due to acquired mitoxantrone resistance in human gastric carcinoma cell line EPG85-257.
A newly established gastric carcinoma cell line (EPG85-257P) exhibited a high sensitivity to mitoxantrone (DHAD) as determined by… 
Highly Cited
1989
Highly Cited
1989
Expression of a human multidrug resistance cDNA (MDR1) in the bone marrow of transgenic mice: resistance to daunomycin-induced leukopenia
The human multidrug resistance gene (MDR1) encodes a drug efflux pump glycoprotein (P-glycoprotein) responsible for resistance to… 
Highly Cited
1983
Highly Cited
1983
Thermodynamics of drug-DNA interactions.
Batch calorimetry, differential scanning calorimetry (DSC), uv/vis absorption spectroscopy, fluorescence spectroscopy, and… 
Highly Cited
1978
Highly Cited
1978
Higher antitumor efficacy of daunomycin when linked to dextran: in vivo and in vitro studies.
Daunomycin was coupled to dextrans of various molecular sizes. The binding to the dextran carriers augmented the therapeutic… 
Highly Cited
1978
Highly Cited
1978
Combination chemotherapy for acute lymphoblastic leukaemia in adults.
Fifty-one adults with acute lymphoblastic leukaemia were entered into a trial of intense initial chemotherapy and early… 
Highly Cited
1978
Highly Cited
1978
DRB-induced premature termination of late adenovirus transcription
Exposure of HeLa cells to 5, 6-dichloro-1-β-D-ribofura-nosylbenzimidazde (DRB) late in the course of adenovirus 2 infection… 
Highly Cited
1975
Highly Cited
1975
A preparative synthesis of 3-amino-2,3,6-trideoxy-L-lyxo-hexose (daunosamine) hydrochloride from D-mannose.
Highly Cited
1966
Highly Cited
1966
Physicochemical properties of complexes between deoxyribonucleic acid and antibiotics which affect ribonucleic acid synthesis (actinomycin, daunomycin, cinerubin, nogalamycin, chormomycin…
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