Daunorubicin

Known as: Daunorubicine, Daunomycin, DNM 
An anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Daunorubicin exhibits cytotoxic activity through… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1954-2017
010020030019542016

Papers overview

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Highly Cited
2012
Highly Cited
2012
BACKGROUND Acute myeloid leukemia (AML) is a heterogeneous disease with respect to presentation and clinical outcome. The… (More)
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Highly Cited
2010
Highly Cited
2010
Chemotherapy for brain glioma has been of limited value due to the inability of transport of drug across the blood-brain barrier… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND A complete remission is essential for prolonging survival in patients with acute myeloid leukemia (AML). Daunorubicin… (More)
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Highly Cited
1999
Highly Cited
1999
-The clinical efficacy of anthracycline antineoplastic agents is limited by a high incidence of severe and usually irreversible… (More)
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Highly Cited
1998
Highly Cited
1998
MCF-7/AdrVp is a multidrug-resistant human breast cancer subline that displays an ATP-dependent reduction in the intracellular… (More)
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Highly Cited
1996
Highly Cited
1996
Many cells are resistant to stimuli that can induce apoptosis, but the mechanisms involved are not fully understood. The… (More)
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Highly Cited
1996
Highly Cited
1996
The nature of the signaling pathway(s) which initiate drug-triggered apoptosis remains largely unknown and is of fundamental… (More)
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Highly Cited
1995
Highly Cited
1995
The sphingomyelin pathway, which is initiated by sphingomyelin hydrolysis to generate the second messenger ceramide, signals… (More)
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Highly Cited
1992
Highly Cited
1992
The purpose of this study was to determine the relative merits of idarubicin and daunorubicin in acute myeloid leukemia (AML… (More)
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Highly Cited
1978
Highly Cited
1978
Uptake and binding of daunorubicin were studied in a sensitive (EHR 2) and in a resistant (EHR 2/DNR+) subline of Ehrlich ascites… (More)
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