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Anthracyclines

Known as: Anthracyclines [Chemical/Ingredient], anthracycline 
Organic compounds that have a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine.
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Doxorubicin (DOX) is widely used as a broad-spectrum anti-tumor anthracycline to treat various cancers. The serious adverse… Expand
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Review
2018
Review
2018
Synovial sarcoma (SS) is a rare sarcoma driven by a translocation between SS18 and SSX 1, 2, or 4. With approximately 800 to 1… Expand
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Highly Cited
2010
Highly Cited
2010
OBJECTIVES The purpose of this study was to evaluate the clinical relevance of anthracycline-induced cardiomyopathy (AC-CMP) and… Expand
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Highly Cited
2009
Highly Cited
2009
UNLABELLED PURPOSE To improve on current standards for breast cancer prognosis and prediction of chemotherapy benefit by… Expand
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Highly Cited
2002
Highly Cited
2002
PURPOSE Docetaxel and capecitabine, a tumor-activated oral fluoropyrimidine, show high single-agent efficacy in metastatic breast… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The HER2 gene, which encodes the growth factor receptor HER2, is amplified and HER2 is overexpressed in 25 to 30… Expand
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Highly Cited
2001
Highly Cited
2001
Background The HER2 gene, which encodes the growth factor receptor HER2, is amplified and HER2 is overexpressed in 25 to 30… Expand
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Review
1999
Review
1999
  • D. Gewirtz
  • Biochemical pharmacology
  • 1999
  • Corpus ID: 10420093
The mechanisms responsible for the antiproliferative and cytotoxic effects of the anthracycline antibiotics doxorubicin… Expand
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Review
1992
Review
1992
  • R. Weiss
  • Seminars in oncology
  • 1992
  • Corpus ID: 46289384
The anthracyclines are the class of antitumor drugs with the widest spectrum of activity in human cancers, and only a few cancers… Expand
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Highly Cited
1991
Highly Cited
1991
OBJECTIVE --To assess the cardiac status of long-term survivors of pediatric malignancies who received chemotherapy, including… Expand
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