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Anthracyclines

Known as: Anthracyclines [Chemical/Ingredient], anthracycline 
Organic compounds that have a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
OBJECTIVES The purpose of this study was to evaluate the clinical relevance of anthracycline-induced cardiomyopathy (AC-CMP) and… Expand
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Review
2005
Review
2005
BACKGROUND Quinquennial overviews (1985-2000) of the randomised trials in early breast cancer have assessed the 5 year and 10… Expand
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Review
2004
Review
2004
The clinical use of anthracyclines like doxorubicin and daunorubicin can be viewed as a sort of double-edged sword. On the one… Expand
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Highly Cited
2002
Highly Cited
2002
PURPOSE Docetaxel and capecitabine, a tumor-activated oral fluoropyrimidine, show high single-agent efficacy in metastatic breast… Expand
Highly Cited
2001
Highly Cited
2001
BACKGROUND The HER2 gene, which encodes the growth factor receptor HER2, is amplified and HER2 is overexpressed in 25 to 30… Expand
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Review
1999
Review
1999
  • D. Gewirtz
  • Biochemical pharmacology
  • 1999
  • Corpus ID: 10420093
The mechanisms responsible for the antiproliferative and cytotoxic effects of the anthracycline antibiotics doxorubicin… Expand
Review
1992
Review
1992
  • R. Weiss
  • Seminars in oncology
  • 1992
  • Corpus ID: 46289384
The anthracyclines are the class of antitumor drugs with the widest spectrum of activity in human cancers, and only a few cancers… Expand
Highly Cited
1991
Highly Cited
1991
OBJECTIVE --To assess the cardiac status of long-term survivors of pediatric malignancies who received chemotherapy, including… Expand
Highly Cited
1986
Highly Cited
1986
In the present study we have used beef heart submitochondrial preparations (BH-SMP) to demonstrate that a component of… Expand
Review
1981
Review
1981
PERHAPS no family of chemotherapeutic agents has been so rapidly accepted as a major therapeutic tool in treating patients with… Expand