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Alkane 1-monooxygenase

Known as: Omega-Hydroxylase, Laurate, Lauric Acid Monooxygenase, Alkane 1 Hydroxylase 
A P450 oxidoreductase that catalyzes the hydroxylation of the terminal carbon of linear hydrocarbons such as OCTANES and FATTY ACIDS in the omega… 
National Institutes of Health

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CYP4A11 geneIn BloodProcess of secretionalkane 1-monooxygenase activity

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CYP4A11 protein, human

Papers overview

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Highly Cited
2010
Highly Cited
2010
DIRECT EVIDENCE FOR AN ENHANCEMENT OF HELIUM IN GIANT STARS IN OMEGA CENTAURI
The double main sequence identified in the globular cluster Omega Centauri has been interpreted using isochrones to indicate a… 
2008
2008
Isolation and characterization of alkane hydroxylases from a metagenomic library of Pacific deep-sea sediment
Two clones 9E7 and 21G8 in a metagenomic library of the east Pacific deep-sea sediment were found to contain alkane hydroxylase… 
2002
2002
Autocatalytic Mechanism and Consequences of Covalent Heme Attachment in the Cytochrome P4504A Family*
The prosthetic heme group in the CYP4A family of cytochrome P450 enzymes is covalently attached to an I-helix glutamic acid… 
Highly Cited
2001
Highly Cited
2001
The kinetic and spectral characterization of the E. coli-expressed mammalian CYP4A7: cytochrome b5 effects vary with substrate.
The CYP4A gene subfamily is composed of a number of genes that encode cytochromes P450 from various species, including human… 
Highly Cited
1999
Highly Cited
1999
Characterization of cytochrome P450 expression in human oesophageal mucosa.
The expression of cytochrome (CYP) P450 enzymes in human oesophageal mucosa was investigated in a total of 25 histologically non… 
1997
1997
Hepatic microsomal enzyme induction, beta-oxidation, and cell proliferation following administration of clofibrate, gemfibrozil, or bezafibrate in the CD rat.
Male and female CD rats were administered one of two dose levels of clofibrate, gemfibrozil, or bezafibrate daily by oral gavage… 
Highly Cited
1994
Highly Cited
1994
Induction of microsomal and peroxisomal enzymes by dehydroepiandrosterone and its reduced metabolite in rats.
Dehydroepiandrosterone (DHEA) given to rodents in pharmacological doses induces several hepatic enzymes including cytochromes… 
Highly Cited
1993
Highly Cited
1993
Solution structure of omega-conotoxin GVIA using 2-D NMR spectroscopy and relaxation matrix analysis.
We report here the solution structure of omega-conotoxin GVIA, a peptide antagonist of the N-type neuronal voltage-sensitive… 
Highly Cited
1992
Highly Cited
1992
Two types of high‐threshold calcium currents inhibited by omega‐conotoxin in nerve terminals of rat neurohypophysis.
1. The neurohypophysis comprises the nerve terminals of hypothalamic neurosecretory cells, which contain arginine vasopressin… 
Highly Cited
1985
Highly Cited
1985
Leukotriene B4 omega-hydroxylase in human polymorphonuclear leukocytes. Partial purification and identification as a cytochrome P-450.
Human polymorphonuclear leukocytes (PMN) not only synthesize and respond to leukotriene B4 (LTB4), but also catabolize this… 
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