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Nitric Oxide: A Review of Its Role in Retinal Function and Disease
Nitric oxide synthase (NOS), the enzyme that catalyzes the formation of nitric oxide from L-arginine, exists in three major isoforms, neuronal, endothelial, and immunologic. Neuronal and endothelialExpand
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Preconditioning provides complete protection against retinal ischemic injury in rats.
PURPOSE The objectives of this study were to examine whether preconditioning can decrease ischemic damage to the retina, by electroretinographic assessment of visual function and by histologicExpand
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Protected environments and prophylactic antibiotics. A prospective controlled study of their utility in the therapy of acute leukemia.
Abstract To reduce the frequency of infection in acute leukemia, we employed isolation and air-filtration facilities ("protected environment") and a prophylactic regimen that included oral nonabsor...
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Complement and immunoglobulins stimulate superoxide production by human leukocytes independently of phagocytosis.
Human peripheral blood polymorphonuclear leukocytes, when exposed to appropriate stimuli, generate significant amounts of superoxide anion (O-.2), a highly reactive molecule which is possiblyExpand
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Thromboxane generation by human peripheral blood polymorphonuclear leukocytes
Human peripheral blood polymorphonuclear leukocytes were stimulated to generate thromboxane B2 in a time- and concentration-dependent fashion upon exposure to serum-treated zymosan particles.Expand
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Ceruloplasmin. A scavenger of superoxide anion radicals.
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Biologically active products of complement and acute lung injury in patients with the sepsis syndrome.
To determine if biologically active products of complement appear during sepsis and to establish the relationship of these components to the respiratory and hemodynamic complications of sepsis, weExpand
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Complement (C5)-derived chemotactic activity accounts for accumulation of polymorphonuclear leukocytes in cerebrospinal fluid of rabbits with pneumococcal meningitis.
Experiments were performed to identify the chemoattractant for polymorphonuclear leukocytes that appears in the cerebrospinal fluid of rabbits with experimental pneumococcal meningitis. MeningitisExpand
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A single amino acid distinguishes the high‐responder from the low‐responder form of Fc receptor II on human monocytes
The low‐affinity Fc receptor on human peripheral blood monocytes (FcγRIIA) is polymorphic with respect to its ability to bind murine IgG1. The two allelic forms of the receptor, high responder (HR)Expand
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Sequences of complementary DNAs that encode the NA1 and NA2 forms of Fc receptor III on human neutrophils.
Two polymorphic forms of Fc receptor III (FcR III) are expressed on human neutrophils. These differ with respect to their apparent molecular masses after digestion with N-glycanase, and with respectExpand
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