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CYP4A11 gene

Known as: CYP4AII, CYTOCHROME P450, SUBFAMILY IVA, POLYPEPTIDE 11, cytochrome P450 family 4 subfamily A member 11 
National Institutes of Health

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Alkane 1-monooxygenaseCYP4A11 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Immunochemical quantification of cynomolgus CYP2J2, CYP4A and CYP4F enzymes in liver and small intestine
Abstract 1. An increasing number of studies have indicated the roles of CYP4 proteins in drug metabolism; however, CYP4… 
2015
2015
Cisplatin-mediated cytotoxicity through inducing CYP4A 11 expression in human renal tubular epithelial cells.
Cisplatin (CP) is a major antineoplastic drug for the treatment of solid tumors, but it has dose-dependent renal tubular toxicity… 
2013
2013
Association between the CYP4A11 T8590C Variant and Essential Hypertension: New Data from Han Chinese and a Meta-Analysis
Objective CYP4A11 oxidizes endogenous arachidonic acid to 20-hydroxyeicosatetraenoic acid, a renal vasoconstrictor and… 
2013
2013
Evaluation of Luminescent P450 Analysis for Directed Evolution of Human CYP4A11
Cytochrome P450 4A11 (CYP4A11) is a fatty acid hydroxylase enzyme expressed in human liver. It catalyzes not only the… 
2011
2011
Cynomolgus macaque CYP4 isoforms are functional, metabolizing arachidonic acid.
Cytochrome P450 (CYP) is important for metabolism of not only xenobiotics such as drugs, but also endogenous compounds including… 
2011
2011
A common polymorphism of CYP4A11 is associated with blood pressure in a Chinese population
Variants of the human CYP4A11, which belongs to the cytochrome P450, family 4, have been reported to be associated with… 
2006
2006
Determination of CYP4A11-catalyzed lauric acid 12-hydroxylation by high-performance liquid chromatography with radiometric detection.
Lauric acid serves as an endogenous substrate for the cytochrome P450 enzyme CYP4A11. A reverse-phase, high-performance liquid… 
2003
2003
Characterization of the CYP4A11 gene, a second CYP4A gene in humans.
2002
2002
Associations between human liver and kidney cadmium content and immunochemically detected CYP4A11 apoprotein.
1999
1999
Homology modeling and substrate binding study of human CYP4A11 enzyme.
Although both bacterial CYP102 (P450BM3) and mammalian CYP4A isozymes share a common function as fatty acid hydroxylases… 
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