ATRIP gene

Known as: ATRIP, ATR-INTERACTING PROTEIN, MGC21482 
This gene is involved in the DNA damage checkpoint.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
ATR and Chk1 are two key protein kinases in the replication checkpoint. Activation of ATR-Chk1 has been extensively investigated… (More)
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Highly Cited
2008
Highly Cited
2008
The ATR (ATM and Rad3-related) kinase and its regulatory partner ATRIP (ATR-interacting protein) coordinate checkpoint responses… (More)
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2008
2008
In this issue of Genes & Development, Mordes and colleagues (pp. 1478-1489) reveal intriguing mechanistic insights into… (More)
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Highly Cited
2006
Highly Cited
2006
ATR is a key regulator of checkpoint responses to incompletely replicated and damaged DNA, but the mechanisms underlying control… (More)
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Highly Cited
2005
Highly Cited
2005
ATR associates with the regulatory protein ATRIP that has been proposed to localize ATR to sites of DNA damage through an… (More)
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Highly Cited
2005
Highly Cited
2005
Ataxia-telangiectasia mutated (ATM), ataxia-telangiectasia and Rad3-related (ATR) and DNA-dependent protein kinase catalytic… (More)
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Highly Cited
2004
Highly Cited
2004
Claspin is necessary for the ATR-dependent activation of Chk1 in Xenopus egg extracts containing incompletely replicated DNA. ATR… (More)
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Review
2004
Review
2004
Disruption of the mechanisms that regulate cell-cycle checkpoints, DNA repair, and apoptosis results in genomic instability and… (More)
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Highly Cited
2003
Highly Cited
2003
The function of the ATR (ataxia-telangiectasia mutated- and Rad3-related)-ATRIP (ATR-interacting protein) protein kinase complex… (More)
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Highly Cited
2001
Highly Cited
2001
The checkpoint kinases ATM (ataxia telangiectasia mutated) and ATR (ATM and Rad3 related) transduce genomic stress signals to… (More)
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