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Cell Cycle Progression

The cell cycle is an ordered set of events. Progression through the stages of cell cycle, including G1-S-G2-M, culminates in cell growth and division… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
The cyclin-dependent kinase (CDK)–RB–E2F axis forms the core transcriptional machinery driving cell cycle progression, dictating… Expand
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Review
2019
Review
2019
The ubiquitin proteasome system (UPS) degrades individual proteins in a highly regulated fashion and is responsible for the… Expand
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Review
2019
Review
2019
Triple negative breast cancer (TNBC), which is typically lack of expression of estrogen receptor (ER), progesterone receptor (PR… Expand
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Review
2019
Review
2019
Aberrant function of cell cycle regulators results in uncontrolled cell proliferation, making them attractive therapeutic targets… Expand
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Review
2006
Review
2006
The Rb protein is a tumor suppressor, which plays a pivotal role in the negative control of the cell cycle and in tumor… Expand
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Review
2003
Review
2003
The PI3K/Akt signal transduction cascade has been investigated extensively for its roles in oncogenic transformation. Initial… Expand
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Review
2003
Review
2003
As its role in tumor progression emerges, the PI3K/PKB (Akt) pathway presents an appealing cancer therapeutic target. Recent… Expand
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Highly Cited
2002
Highly Cited
2002
The E2F transcription factor family is known to play a key role in the timely expression of genes required for cell cycle… Expand
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Highly Cited
1995
Highly Cited
1995
Members of the Rho family of small guanosine triphosphatases (GTPases) regulate the organization of the actin cytoskeleton; Rho… Expand
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Highly Cited
1993
Highly Cited
1993
A cascade of events is triggered upon the addition of growth factor to quiescent mammalian cells, which ultimately restarts… Expand
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