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APRT gene

Known as: ADENINE PHOSPHORIBOSYLTRANSFERASE, APRT, Adenine Phosphoribosyltransferase Gene 
This gene plays a role in the purine salvage pathway.
National Institutes of Health

Related topics

Related topics

3 relations
Adenine PhosphoribosyltransferaseNucleotide Metabolismglycosylation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
The role of the Corynebacterium glutamicum rel gene in (p)ppGpp metabolism.
To investigate the metabolism of (p)ppGpp in amino-acid-producing coryneform bacteria, a PCR-based strategy using degenerate… 
Highly Cited
1996
Highly Cited
1996
A relA/spoT Homologous Gene from Streptomyces coelicolor A3(2) Controls Antibiotic Biosynthetic Genes (*)
A 0.972-kilobase pair DNA fragment from Streptomyces lividans that induces the production of the blue-pigmented antibiotic… 
Highly Cited
1996
Highly Cited
1996
Other transgenic mutation assays: APRT: A versatile in vivo resident reporter of local mutation and loss of heterozygosity
We describe an in vivo mutagenesis model that utilizes reverse mutation and forward mutation at the endogenous Aprt locus… 
Highly Cited
1993
Highly Cited
1993
Anaerobic control of denitrification in Pseudomonas stutzeri escapes mutagenesis of an fnr-like gene
The synthesis of proteins necessary for the respiratory reduction of nitrate to dinitrogen is induced in most denitrifying… 
Highly Cited
1987
Highly Cited
1987
Human adenine phosphoribosyltransferase. Identification of allelic mutations at the nucleotide level as a cause of complete deficiency of the enzyme.
This study reports the first demonstration of specific mutations leading to human adenine phosphoribosyltransferase (APRT… 
Highly Cited
1980
Highly Cited
1980
Mutagenicity testing in mammalian cells. I. Derivation of a Chinese hamster ovary cell line heterozygous for the adenine phosphoribosyltransferase and thymidine kinase loci.
Highly Cited
1979
Highly Cited
1979
DNA crosslinking, sister-chromatid exchange and specific-locus mutations.
Highly Cited
1971
Highly Cited
1971
The regulation of purine utilization in bacteria. I. Purification of adenine phosphoribosyltransferase from Escherichia coli K12 and control of activity by nucleotides.
Abstract The adenine phosphoribosyltransferase of Escherichia coli K-12 is markedly derepressed under cultural conditions which… 
Highly Cited
1969
Highly Cited
1969
Adenine phosphoribosyltransferase from monkey liver. Specificity and properties.
Highly Cited
1966
Highly Cited
1966
Purine-phosphoribosyltransferase activities in rat and mouse tissues and in Ehrlich ascites-tumour cells.
1. The activities of adenine phosphoribosyltransferase and hypoxanthine phosphoribosyltransferase in extracts of rat and mouse… 
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