Adenine Phosphoribosyltransferase

Known as: APRTase, EC 2.4.2.7, AMP Pyrophosphorylase 
An enzyme catalyzing the formation of AMP from adenine and phosphoribosylpyrophosphate. It can act as a salvage enzyme for recycling of adenine into… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2017
010203019652017

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2001
2001
Adenine phosphoribosyltransferase (APRT) deficiency is a rarely diagnosed cause of renal allograft dysfunction. We report the… (More)
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1996
1996
Adenine phosphoribosyltransferase (APRT) deficiency in humans is an autosomal recessive syndrome characterized by the urinary… (More)
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1994
1994
The apt gene, coding for adenine phosphoribosyltransferase (APRT), has been isolated from the plant Arabidopsis thaliana. Data… (More)
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Highly Cited
1994
Highly Cited
1994
Animal somatic cell DNA is characterized by a bimodal pattern of methylation: tissue-specific genes are methylated in most cell… (More)
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Highly Cited
1991
Highly Cited
1991
Reports describing short (< 20 bp) gene deletions causing human genetic disease were collated in order to study underlying… (More)
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1989
1989
We have developed a system that permits analysis of targeted homologous recombination at an endogenous, chromosomal gene locus in… (More)
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Highly Cited
1982
Highly Cited
1982
The effect of DNA methylation on the expression of the hamster adenine phosphoribosyltransferase (aprt) gene in mouse cells has… (More)
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Highly Cited
1979
Highly Cited
1979
In this report, we demonstrate the feasibility of transforming mouse cells deficient in adenine phosphoribosyltransferase (aprt… (More)
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1977
1977
We studied the clinical and biochemical manifestations of complete adenine phosphoribosyltransferase deficiency in the kindred of… (More)
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1968
1968
A deficiency of adenine phosphoribosyltransferase (A-PRTase) is described in four members in three generations of one family. A… (More)
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