FAQ

Adenine Phosphoribosyltransferase

Known as: APRTase, EC 2.4.2.7, AMP Pyrophosphorylase 
An enzyme catalyzing the formation of AMP from adenine and phosphoribosylpyrophosphate. It can act as a salvage enzyme for recycling of adenine into… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2017
010203019652017

Related topics

Related topics

22 relations
APRT geneAdenosine MonophosphateCarbohydrate MetabolismEnzyme Gene
(More)

Narrower (1)

Adenine phosphoribosyltransferase deficiency

Broader (1)

pentosyltransferase

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Adenine Phosphoribosyltransferase
physiological aspects
Adenosine Monophosphate
Carbohydrate Metabolism
chemical synthesis
Nucleotide Metabolism

Papers overview

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2001
2001
Adenine phosphoribosyltransferase deficiency and renal allograft dysfunction.
Adenine phosphoribosyltransferase (APRT) deficiency is a rarely diagnosed cause of renal allograft dysfunction. We report the… (More)
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1996
1996
Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis.
Adenine phosphoribosyltransferase (APRT) deficiency in humans is an autosomal recessive syndrome characterized by the urinary… (More)
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1994
1994
The adenine phosphoribosyltransferase-encoding gene of Arabidopsis thaliana.
The apt gene, coding for adenine phosphoribosyltransferase (APRT), has been isolated from the plant Arabidopsis thaliana. Data… (More)
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Highly Cited
1994
Highly Cited
1994
Sp1 elements protect a CpG island from de novo methylation.
Animal somatic cell DNA is characterized by a bimodal pattern of methylation: tissue-specific genes are methylated in most cell… (More)
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Highly Cited
1991
Highly Cited
1991
Gene deletions causing human genetic disease: mechanisms of mutagenesis and the role of the local DNA sequence environment
Reports describing short (< 20 bp) gene deletions causing human genetic disease were collated in order to study underlying… (More)
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1989
1989
Targeted homologous recombination at the endogenous adenine phosphoribosyltransferase locus in Chinese hamster cells.
We have developed a system that permits analysis of targeted homologous recombination at an endogenous, chromosomal gene locus in… (More)
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Highly Cited
1982
Highly Cited
1982
In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells.
The effect of DNA methylation on the expression of the hamster adenine phosphoribosyltransferase (aprt) gene in mouse cells has… (More)
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Highly Cited
1979
Highly Cited
1979
DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.
In this report, we demonstrate the feasibility of transforming mouse cells deficient in adenine phosphoribosyltransferase (aprt… (More)
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1977
1977
Complete deficiency of adenine phosphoribosyltransferase: report of a family.
We studied the clinical and biochemical manifestations of complete adenine phosphoribosyltransferase deficiency in the kindred of… (More)
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1968
1968
Adenine phosphoribosyltransferase deficiency: a previously undescribed genetic defect in man.
A deficiency of adenine phosphoribosyltransferase (A-PRTase) is described in four members in three generations of one family. A… (More)
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