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Adenine Phosphoribosyltransferase

Known as: APRTase, EC 2.4.2.7, AMP Pyrophosphorylase 
An enzyme catalyzing the formation of AMP from adenine and phosphoribosylpyrophosphate. It can act as a salvage enzyme for recycling of adenine into… 
National Institutes of Health

Related topics

Related topics

24 relations
APRT geneAdenine phosphoribosyltransferase:CCnc:Pt:RBC:QnAdenine phosphoribosyltransferase:CCnt:Pt:Trophoblasts:QnAdenosine Monophosphate
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Narrower (1)

Adenine phosphoribosyltransferase deficiency

Broader (1)

pentosyltransferase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Biological activities from extracts of endophytic fungi isolated from Viguiera arenaria and Tithonia diversifolia.
A total of 39 endophytic fungi have been isolated from Viguiera arenaria and Tithonia diversifolia, both collected in São Paulo… 
Highly Cited
2002
Highly Cited
2002
Adenine phosphoribosyltransferase isoforms of Arabidopsis and their potential contributions to adenine and cytokinin metabolism.
Adenine phosphoribosyltransferase (APT; EC 2.4.2.7) is a constitutively expressed enzyme involved in the one-step salvage of… 
Highly Cited
1994
Highly Cited
1994
Analysis of repair of cyclobutane pyrimidine dimers and pyrimidine 6-4 pyrimidone photoproducts in transcriptionally active and inactive genes in Chinese hamster cells.
Highly Cited
1981
Highly Cited
1981
Dependence of adenine production upon polyamine synthesis in cultured human lymphoblasts.
Highly Cited
1980
Highly Cited
1980
Validation of conditions for efficient detection of HPRT and APRT mutations in suspension-cultured Chinese hamster ovary cells.
Highly Cited
1979
Highly Cited
1979
DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.
In this report, we demonstrate the feasibility of transforming mouse cells deficient in adenine phosphoribosyltransferase (aprt… 
Highly Cited
1978
Highly Cited
1978
Human α-globin gene expression following chromosomal dependent gene transfer into mouse erythroleukemia cells
Highly Cited
1974
Highly Cited
1974
Mutants of cultured chinese hamster cells deficient in adenine phosphoribosyl transferase.
1969
1969
Adenine phosphoribosyltransferase from monkey liver. Specificity and properties.
Abstract The structural requirements for the binding of purines to adenine phosphoribosyltransferase from monkey liver were… 
Highly Cited
1967
Highly Cited
1967
A specific enzyme defect in gout associated with overproduction of uric acid.
Gout is classed among the inborn errors of metabolism,1 but unlike the majority of such disorders no single specific metabolic… 
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