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Adenine Phosphoribosyltransferase

Known as: APRTase, EC 2.4.2.7, AMP Pyrophosphorylase 
An enzyme catalyzing the formation of AMP from adenine and phosphoribosylpyrophosphate. It can act as a salvage enzyme for recycling of adenine into… Expand
National Institutes of Health

Related topics

Related topics

24 relations
APRT geneAdenine phosphoribosyltransferase:CCnc:Pt:RBC:QnAdenine phosphoribosyltransferase:CCnt:Pt:Trophoblasts:QnAdenosine Monophosphate
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Narrower (1)

Adenine phosphoribosyltransferase deficiency

Broader (1)

pentosyltransferase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Biological activities from extracts of endophytic fungi isolated from Viguiera arenaria and Tithonia diversifolia.
A total of 39 endophytic fungi have been isolated from Viguiera arenaria and Tithonia diversifolia, both collected in São Paulo… Expand
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Highly Cited
2001
Highly Cited
2001
Insertion of a Telomere Repeat Sequence into a Mammalian Gene Causes Chromosome Instability
ABSTRACT Telomere repeat sequences cap the ends of eucaryotic chromosomes and help stabilize them. At interstitial sites, however… Expand
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Highly Cited
1994
Highly Cited
1994
The adenine phosphoribosyltransferase-encoding gene of Arabidopsis thaliana.
The apt gene, coding for adenine phosphoribosyltransferase (APRT), has been isolated from the plant Arabidopsis thaliana. Data… Expand
Highly Cited
1989
Highly Cited
1989
Molecular basis of spontaneous mutation at the aprt locus of hamster cells.
Mutations occurring spontaneously at the hamster aprt locus were examined at the base-pair level by amplifying target sequences… Expand
Highly Cited
1986
Highly Cited
1986
Nucleotide sequence and deduced amino acid sequence of Escherichia coli adenine phosphoribosyltransferase and comparison with other analogous enzymes.
The Escherichia coli apt gene has been analyzed and its nucleotide (nt) sequence and the deduced amino acid (aa) sequence… Expand
Highly Cited
1979
Highly Cited
1979
DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.
In this report, we demonstrate the feasibility of transforming mouse cells deficient in adenine phosphoribosyltransferase (aprt… Expand
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Highly Cited
1978
Highly Cited
1978
Human α-globin gene expression following chromosomal dependent gene transfer into mouse erythroleukemia cells
Abstract We have used the genetic marker, adenine phosphoribosyl transferase (APRT), an enzyme known to be on human chromosome 16… Expand
Highly Cited
1974
Highly Cited
1974
Mutants of cultured chinese hamster cells deficient in adenine phosphoribosyl transferase.
Abstract Spontaneous mutants of cultured Chinese hamster cells (line CHO) deficient in APRT have been isolated by selection in 8… Expand
Highly Cited
1967
Highly Cited
1967
A specific enzyme defect in gout associated with overproduction of uric acid.
Gout is classed among the inborn errors of metabolism,1 but unlike the majority of such disorders no single specific metabolic… Expand
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Highly Cited
1966
Highly Cited
1966
Kinetic studies of adenine phosphoribosyltransferase.
Abstract The mechanism of reaction of adenine phosphoribosyl-transferase from Ehrlich ascites tumor cells was investigated… Expand
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