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Adenine Phosphoribosyltransferase

Known as: APRTase, EC 2.4.2.7, AMP Pyrophosphorylase 
An enzyme catalyzing the formation of AMP from adenine and phosphoribosylpyrophosphate. It can act as a salvage enzyme for recycling of adenine into… 
National Institutes of Health

Related topics

Related topics

24 relations
APRT geneAdenine phosphoribosyltransferase:CCnc:Pt:RBC:QnAdenine phosphoribosyltransferase:CCnt:Pt:Trophoblasts:QnAdenosine Monophosphate

Narrower (1)

Adenine phosphoribosyltransferase deficiency

Broader (1)

pentosyltransferase

Papers overview

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1996
1996
Purification and characterization of an adenine phosphoribosyltransferase from rubber tree latex. Physiological implications
Adenine phosphoribosyltransferase (APRT; EC 2.4.2.7) catalyses AMP and pyrophosphate (PPi) production from adenine and 5… 
1983
1983
High-frequency structural gene deletion as the basis for functional hemizygosity of the adenine phosphoribosyltransferase locus in Chinese hamster ovary cells.
The CHO-AT3-2 Chinese hamster ovary cell line is functionally hemizygous for the adenine phosphoribosyltransferase (APRT; EC 2.4… 
1982
1982
Adenine phosphoribosyltransferase in patients with disorders of purine and pyrimidine metabolism.
Elevated levels of APRT activity are found in erythrocytes from most patients with a primary deficiency of HPRT. A twofold… 
1980
1980
The differences in purine metabolism between T and B lymphocytes.
In this study enzyme activities involved in purine metabolism were measured in T and B lymphocytes separated by E and EAC… 
Highly Cited
1971
Highly Cited
1971
A new reduced human-mouse somatic cell hybrid containing the human gene for adenine phosphoribosyltransferase.
A system that selects for the gene directing synthesis of the enzyme adenine phosphoribosyltransferase (APRT) uses the antibiotic… 
1970
1970
Studies of the binding of adenine to adenine phosphoribosyltransferase
The groups on adenine phosphoribosyltransferase and on adenine which are involved in the binding of this substrate were… 
1970
1970
Mechanisms of inhibition of adenine phosphoribosyltransferase by adenine nucleosides and nucleotides.
Kinetic studies of the inhibition of adenine phosphoribosyltransferase by adenine 6′-deoxyallofuranoside and 2′-deoxyadenylate… 
1968
1968
Kinetic studies of mutant human erythrocyte adenine phosphoribosyltransferases.
The kinetic constants and reaction mechanism of human erythrocyte adenine phosphoribosyltransferase from individuals whose enzyme… 
1967
1967
Stimulation of adenine phosphoribosyltransferase by adenosine triphosphate and other nucleoside triphosphates.
1. Adenine phosphoribosyltransferase was protected from inactivation on heating at 55 degrees by the presence of 5-phosphoribosyl… 
1966
1966
Inhibition of purine phosphoribosyltransferases from Ehrlich ascites-tumour cells by purine nucleotides.
1. The purine bases adenine, hypoxanthine and guanine were rapidly incorporated into the nucleotide fraction of Ehrlich ascites…