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Adenine Phosphoribosyltransferase

Known as: APRTase, EC 2.4.2.7, AMP Pyrophosphorylase 
An enzyme catalyzing the formation of AMP from adenine and phosphoribosylpyrophosphate. It can act as a salvage enzyme for recycling of adenine into… Expand
National Institutes of Health

Related topics

Related topics

24 relations
APRT geneAdenine phosphoribosyltransferase:CCnc:Pt:RBC:QnAdenine phosphoribosyltransferase:CCnt:Pt:Trophoblasts:QnAdenosine Monophosphate
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Narrower (1)

Adenine phosphoribosyltransferase deficiency

Broader (1)

pentosyltransferase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Adenine phosphoribosyltransferase isoforms of Arabidopsis and their potential contributions to adenine and cytokinin metabolism.
Adenine phosphoribosyltransferase (APT; EC 2.4.2.7) is a constitutively expressed enzyme involved in the one-step salvage of… Expand
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1999
1999
Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani.
The enzyme adenine phosphoribosyltransferase (APRT) functions to salvage adenine by converting it to adenosine-5-monophosphate… Expand
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1996
1996
APRT: a versatile in vivo resident reporter of local mutation and loss of heterozygosity.
We describe an in vivo mutagenesis model that utilizes reverse mutation and forward mutation at the endogenous Aprt locus… Expand
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1996
1996
A second form of adenine phosphoribosyltransferase in Arabidopsis thaliana with relative specificity towards cytokinins.
Adenine phosphoribosyltransferase (APRTase) is an important enzyme for its ability to convert adenine, a byproduct of many… Expand
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Highly Cited
1994
Highly Cited
1994
The adenine phosphoribosyltransferase-encoding gene of Arabidopsis thaliana.
The apt gene, coding for adenine phosphoribosyltransferase (APRT), has been isolated from the plant Arabidopsis thaliana. Data… Expand
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1991
1991
Metabolism of Benzyladenine is Impaired in a Mutant of Arabidopsis thaliana Lacking Adenine Phosphoribosyltransferase Activity.
Formation of the riboside-5'-monophosphate is a general feature of the metabolism of cytokinins in plants. As part of a study of… Expand
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1989
1989
Targeted homologous recombination at the endogenous adenine phosphoribosyltransferase locus in Chinese hamster cells.
We have developed a system that permits analysis of targeted homologous recombination at an endogenous, chromosomal gene locus in… Expand
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1986
1986
Nucleotide sequence and deduced amino acid sequence of Escherichia coli adenine phosphoribosyltransferase and comparison with other analogous enzymes.
The Escherichia coli apt gene has been analyzed and its nucleotide (nt) sequence and the deduced amino acid (aa) sequence… Expand
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Highly Cited
1979
Highly Cited
1979
DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.
In this report, we demonstrate the feasibility of transforming mouse cells deficient in adenine phosphoribosyltransferase (aprt… Expand
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Highly Cited
1967
Highly Cited
1967
A specific enzyme defect in gout associated with overproduction of uric acid.
Gout is classed among the inborn errors of metabolism,1 but unlike the majority of such disorders no single specific metabolic… Expand
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