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Biological activities from extracts of endophytic fungi isolated from Viguiera arenaria and Tithonia diversifolia.
TLDR
A total of 39 endophytic fungi have been isolated from Viguiera arenaria and Tithonia diversifolia, both collected in São Paulo State, Brazil, and nectriapyrone showed relevant cytotoxic activity against both human T leukemia and melanoma tumor cell lines.
Endophytic Fungi: Natural Products, Enzymes and Biotransformation Reactions
TLDR
Recent data on endophytes research as a source of novel and bioactive natural products, as producers of enzymes and their use on biotransformation processes are summarized.
Endophytic fungi as models for the stereoselective biotransformation of thioridazine
TLDR
The stereoselective kinetic biotransformation of thioridazine, a phenothiazine neuroleptic drug, by endophytic fungi was investigated, with results indicating that mono-2-sulfoxidation occurred in higher ratio and frequency.
Azaphilones from the endophyte Chaetomium globosum.
TLDR
The structure elucidation and the assignment of the relative configurations of the new natural products were based on detailed NMR and MS spectroscopic analyses and the antibiotic activity of the compounds was evaluated using an in vivo Caenorhabditis elegans infection model.
Hydrophobic Nanoprecipitates of β-Cyclodextrin/Avermectins Inclusion Compounds Reveal Insecticide Activity against Aedes aegypti Larvae and Low Toxicity against Fibroblasts.
TLDR
The inclusion of EPRI in βCD increased its larval toxicity and reduced its human cytotoxicity, while for IVER/βCD no beneficial effect was observed upon inclusion, which has great potential as an insecticide against A. aegypti larvae with high human safety.
Identification of Alkaloids from Hippeastrum aulicum (Ker Gawl.) Herb. (Amaryllidaceae) Using CGC-MS and Ambient Ionization Mass Spectrometry (PS-MS and LS-MS)
Amaryllidaceae alkaloids are well-known isoquinolines which have demonstrated a wide range of biological activities such as antiviral, anticancer, acetylcholinesterase inhibition, antimalarial, among
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