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AKR1C1 protein, human

Known as: Type II 3-Alpha-Hydroxysteroid Dehydrogenase, aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase), human, Chlordecone Reductase Homolog HAKRC 
Aldo-keto reductase family 1 member C1 (323 aa, ~37 kDa) is encoded by the human AKR1C1 gene. This protein is involved in the conversion of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Polycyclic aromatic hydrocarbons (PAHs) are tobacco carcinogens implicated in the causation of human lung cancer. Metabolic… Expand
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Highly Cited
2006
Highly Cited
2006
Pyrene degradation is known in bacteria. In this study, Mycobacterium sp. strain KMS was used to study the metabolites produced… Expand
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Highly Cited
2003
Highly Cited
2003
Prostaglandins are important regulators of reproductive function. In particular, prostaglandin F2 alpha (PGF(2 alpha)) is… Expand
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1997
1997
Polycyclic aromatic hydrocarbons require metabolic activation in order to exert their biological activity initiated by DNA… Expand
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1995
1995
The prostaglandin-E2 9-reductase (PGE2 9-reductase) activity in the corpus luteum of rabbits corresponds to a cytosolic, NADPH… Expand
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1990
1990
PRL is known to be a hormone carrying luteotropic action in rats and enhances progesterone secretion by suppressing 20 alpha… Expand
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1989
1989
Two dibenzofuran degrading bacteria, Brevibacterium strain DPO 1361 and strain DPO 220, were found to utilize fluorene as sole… Expand
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1985
1985
Vasoactive intestinal peptide (VIP) and VIPergic nerve fibers are present in the ovaries of several mammalian species, suggesting… Expand
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1981
1981
The mechanism by which gonadotropin-releasing hormone (GnRH) inhibits ovarian progesterone production was investigated by… Expand
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1979
1979
THE enigma of how inert chemicals can exert potent mutagenic, carcinogenic, allergenic and cytotoxic effects has been much… Expand
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