FAQ

AKR1C2 protein, human

Known as: aldo-keto reductase family 1, member C2 protein, human, Aldo-Keto Reductase Family 1 Member C2, Type III 3-Alpha-Hydroxysteroid Dehydrogenase 
Aldo-keto reductase family 1 member C2 (323 aa, ~37 kDa) is encoded by the human AKR1C2 gene. This protein plays a role in the metabolism of steroid… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2017
01219772017

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12 relations
AKR1C1 protein, humanAKR1C2 geneAKR1C3 protein, humanAdrenal Glands
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Broader (1)

Hydroxysteroid Dehydrogenases

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
AKR1C2 protein, human
Adrenal Glands
Oxidation-Reduction
Cytoplasm
Hydroxysteroid Dehydrogenases
xenobiotic metabolism

Papers overview

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2015
2015
Angiotensin II modification by decomposition products of linoleic acid-derived lipid hydroperoxide.
Polyunsaturated fatty acids are highly susceptible to oxidation induced by reactive oxygen species and enzymes, leading to the… (More)
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2014
2014
Effects of major transporter and metabolizing enzyme gene polymorphisms on carbamazepine metabolism in Chinese patients with epilepsy.
AIM The present study aimed to evaluate the effects of SNPs of major transporter and metabolizing enzyme genes on carbamazepine… (More)
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2012
2012
Proteomics-based identification of secreted protein dihydrodiol dehydrogenase 2 as a potential biomarker for predicting cisplatin efficacy in advanced NSCLC patients.
BACKGROUND AND PURPOSE Cisplatin is the major agent in the standard first-line chemotherapy for NSCLC. However, only a small… (More)
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2010
2010
[Modified serum-guided immunoblotting for differential proteomic study of prostate cancer].
OBJECTIVE To search for a new method of screening for molecular targets for androgen-dependent prostate cancer. METHODS We… (More)
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2008
2008
Transcriptional regulation of aldo-keto reductase 1C1 in HT29 human colon cancer cells resistant to methotrexate: role in the cell cycle and apoptosis.
While studying differentially expressed genes between sensitive and 10(-5)M Methotrexate (MTX) resistant HT29 human colon cancer… (More)
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2000
2000
Development of daunorubicin resistance in tumour cells by induction of carbonyl reduction.
A resistant descendant of the human stomach carcinoma cell line EPG85-257 was selected in the presence of increasing… (More)
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2000
2000
Simultaneous stereoselective high-performance liquid chromatographic determination of 10-hydroxycarbazepine and its metabolite carbamazepine-10,11-trans-dihydrodiol in human urine.
An enantioselective HPLC method for the simultaneous determination of the concentration of the enantiomers of the oxcarbazepine… (More)
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1996
1996
Purification and characterization of chlorobenzenecis-dihydrodiol dehydrogenase fromXanthobacter flavus 14p1
Chlorobenzenecis-dihydrodiol dehydrogenase was purified to homogeneity fromXanthobacter flavus 14p1, which used 1,4… (More)
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1995
1995
Frameshift mutation in codon 176 of the p53 gene in rat esophageal epithelial cells transformed by benzo[a]pyrene dihydrodiol.
Mutations in the p53 tumor suppressor gene have been associated with exposure to environmental chemical carcinogens. Cultured rat… (More)
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1994
1994
Structure of a gene coding for human dihydrodiol dehydrogenase/bile acid-binding protein.
The structure and sequence of the gene (DD/BABP) encoding a human dihydrodiol dehydrogenase/bile acid-binding protein (DD/BABP… (More)
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