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AKR1C2 protein, human

Known as: aldo-keto reductase family 1, member C2 protein, human, Aldo-Keto Reductase Family 1 Member C2, Type III 3-Alpha-Hydroxysteroid Dehydrogenase 
Aldo-keto reductase family 1 member C2 (323 aa, ~37 kDa) is encoded by the human AKR1C2 gene. This protein plays a role in the metabolism of steroid… 
National Institutes of Health

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12 relations
AKR1C1 protein, humanAKR1C2 geneAKR1C3 protein, humanAdrenal Glands

Broader (1)

Hydroxysteroid Dehydrogenases

Papers overview

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2013
2013
Identi fi cation of Stable Benzo [ a ] pyrene-7 , 8-dione-DNA Adducts in Human Lung Cells
Metabolic activation of the proximate carcinogen benzo[a]pyrene-7,8-trans-dihydrodiol (B[a]P-7,8-transdihydrodiol) by aldo-keto… 
2012
2012
In-vitro Study of Tamarindus Indica Linn. Against Naphthalene- Induced Cataractogenesis by Using Isolated Goat Lenses
Goat lens are incubated in TC-199 medium containing naphthalene metabolite solution to evaluate the role of naphthalene in the… 
2003
2003
Expression of dihydrodiol dehydrogenase 2 in prostate cancer and its significance
Objective To study the expression of dihydrodiol dehydrogenase (DD) in prostate cancer and its significance. Methods With… 
2000
2000
Cytochrome P 4501 B 1 Mediates Induction of Bone Marrow Cytotoxicity and Preleukemia Cells in Mice Treated with 7 , 12-Dimethylbenz [ a ] anthracene 1
Humans are exposed to polycyclic aromatic hydrocarbons (PAHs) through many environmental pollutants, especially cigarette smoke… 
1995
1995
Characterization of DNA adducts formed by anti-benzo[g]chrysene 11,12-dihydrodiol 13,14-epoxide.
The anti-11,12-dihydrodiol 13,14-epoxide of benzo[g]chrysene, a fjord-region-containing hydrocarbon, was found to react with DNA… 
1990
1990
[The role of secondary metabolism in formation of benz(a)pyrene dihydrodiol profile in microsome membranes].
4,5-, 7,8- and 9,10-dihydrodiols of benz(a)pyrene (BP) were separated by thin-layer chromatography and their influence on BP… 
1987
1987
Radiochemical detection of dihydrodiol dehydrogenase: distribution of the enzyme in male Sprague-Dawley rat tissues and its sensitivity to inhibition by indomethacin and 6-medroxyprogesterone acetate…
Dihydrodiol dehydrogenase (EC 1.3.1.20) catalyzes the NADP+-dependent oxidation of (-)-7R,8R-dihydroxy-dihydro-benzo(a)pyrene and… 
1985
1985
Rates of hydrolysis and extents of DNA binding of 5-methylchrysene dihydrodiol epoxides.
The rates of hydrolysis in the absence and presence of native and denatured DNA, and the extents of DNA binding of five… 
1981
1981
Time course of oxidative benz[a]anthracene metabolism by liver microsomes of normal and PCB-treated rats.
The time course for the oxidative metabolism of benz[a]anthracene by liver microsomes of normal, 3,3',4,4'-tetrachlorobiphenyl… 
1974
1974
Purification andPropeties of(+)-cis-Naphthal ene Dihydrodiol Dehydrogenase ofPseudomonas putida