AF-4 protein

Known as: Trithorax Homolog 2, Protein AF-4, MLLT2 
AF4/FMR2 family member 1 (1210 aa, ~131 kDa) is encoded by the human AFF1 gene. This protein may be involved in the regulation of transcription.
National Institutes of Health

Papers overview

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2012
2012
Systemic lupus erythematosus (SLE) is an autoimmune disease that causes multiple organ damage. Although recent genome-wide… (More)
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Highly Cited
2009
Highly Cited
2009
Aggregation of monoclonal antibodies can be induced by freeze-thawing and elevated temperature, typical stress factors during… (More)
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2007
Highly Cited
2007
AF4 gene, frequently translocated with mixed-lineage leukemia (MLL) in childhood acute leukemia, encodes a putative… (More)
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2006
Highly Cited
2006
Chromosomal rearrangements of the human MLL gene are a hallmark for aggressive (high-risk) pediatric, adult and therapy… (More)
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2005
Highly Cited
2005
Mixed lineage leukemia (MLL) fusion proteins are derived from translocations at 11q23 that occur in aggressive subtypes of… (More)
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2004
2004
The MLL gene is involved in translocations associated with both acute lymphoblastic and acute myelogenous leukemia. These… (More)
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1999
1999
Infant acute lymphoblastic leukemia (ALL) with MLL gene rearrangements is characterized by early pre-B phenotype (CD10(-)/CD19… (More)
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1998
1998
BACKGROUND Cells producing a T(H2)-cytokine profile play an important role in the onset and maintenance of atopic diseases, and… (More)
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1993
Highly Cited
1993
T cells control the majority of antigen-specific immune responses. Therefore, influencing the activation of the T-cell response… (More)
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1988
Highly Cited
1988
Two mAb were used to develop new techniques for the purification and quantitation of the major feline salivary allergen, Felis… (More)
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