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AF-4 protein

Known as: Trithorax Homolog 2, Protein AF-4, MLLT2 
AF4/FMR2 family member 1 (1210 aa, ~131 kDa) is encoded by the human AFF1 gene. This protein may be involved in the regulation of transcription.
National Institutes of Health

Related topics

Related topics

10 relations
AF5q31 proteinAFF1 geneAFF1 wt AlleleAFF4 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Common chromatin structures at breakpoint cluster regions may lead to chromosomal translocations found in chronic and acute leukemias
The t(9;22) BCR/ABL fusion is associated with over 90% of chronic myelogenous and 25% of acute lymphocytic leukemia. Chromosome… 
2005
2005
Measurements of the transverse emittance at the VUV-FEL
The TESLA Test Facility (TTF) linear accelerator (linac) at DESY has been extended to drive a new Free Electron Laser facility… 
2002
2002
High-level expression of immunoreactive recombinant cat allergen (Fel d 1): Targeting to antigen-presenting cells.
BACKGROUND Cat allergen Fel d 1 is a heterodimer encoded by 2 separate genes that has been difficult to produce as a fully… 
2001
2001
Proliferation and release of IL-5 and IFN-gamma by peripheral blood mononuclear cells from cat-allergic asthmatics and rhinitics, non-cat-allergic asthmatics, and normal controls to peptides derived…
BACKGROUND In general, T cells from normal, nonatopic individuals respond to aeroallergens with synthesis and release of IFN… 
2001
2001
First Observation of z-Dependent Electron-Beam Microbunching Using Coherent Transition Radiation.
We report the first measurements of the electron-beam microbunching z dependence in a self-amplified spontaneous-emission (SASE… 
2001
2001
Reduced intracellular survival of Helicobacter pylori vacA mutants in comparison with their wild-types indicates the role of VacA in pathogenesis.
The vacuolating cytotoxin VacA of Helicobacter pylori plays an important but yet unknown role in pathogenesis. We studied the… 
2000
2000
A Novel, Non-High-Dilution Method for Preparation of 1,1,2,2,9,9,10,10-Octafluoro
A novel synthesis of octafluoro[2.2]paracyclophane (AF4), one that remarkably does not require the use of high dilution… 
Highly Cited
1999
Highly Cited
1999
AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23).
Infant acute lymphoblastic leukemia (ALL) with MLL gene rearrangements is characterized by early pre-B phenotype (CD10(-)/CD19… 
Highly Cited
1998
Highly Cited
1998
Immunotherapy with Fel d 1 peptides decreases IL-4 release by peripheral blood T cells of patients allergic to cats.
1994
1994
Detection of HRX-FEL fusion transcripts in pre-pre-B-ALL with and without cytogenetic demonstration of t(4;11).
The t(4;11)(q21;q23) characterizes a distinct clinical entity of childhood and adult acute lymphoblastic leukemia (ALL) with a… 
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