AFF4 gene

Known as: AF4/FMR2 family member 4, MCEF, AFF4 
This gene plays a regulatory role in transcription and is involved in male germ cell differentiation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2016
024620022016

Papers overview

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2015
2015
Transcriptional elongation is critical for gene expression regulation during embryogenesis. The super elongation complex (SEC… (More)
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2014
2014
Developing anti-viral therapies targeting HIV-1 transcription has been hampered by the limited structural knowledge of the… (More)
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2014
2014
Superelongation complexes (SECs) are essential for transcription elongation of many human genes, including the integrated HIV-1… (More)
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2013
2013
The HIV-1 Tat protein stimulates viral gene expression by recruiting human transcription elongation complexes containing P-TEFb… (More)
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2013
2013
Human positive transcription elongation factor b (P-TEFb) phosphorylates RNA polymerase II and regulatory proteins to trigger… (More)
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Highly Cited
2010
Highly Cited
2010
Chromosomal translocations involving the MLL gene are associated with infant acute lymphoblastic and mixed lineage leukemia… (More)
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Highly Cited
2010
Highly Cited
2010
Recruitment of the P-TEFb kinase by HIV-1 Tat to the viral promoter triggers the phosphorylation and escape of RNA polymerase II… (More)
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Highly Cited
2010
Highly Cited
2010
HIV-1 transactivator Tat has greatly contributed to our understanding of transcription elongation by RNAPII. We purified HIV-1… (More)
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2006
2006
Ameboid microglial cells migrate tangentially on the vitreal part of quail embryo retinas by crawling on Müller cell end-feet… (More)
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2002
2002
Positive transcription elongation factor-b (P-TEFb) contains CDK9 and cyclin T(1). P-TEFb was affinity purified from a stably… (More)
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