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AFF1 gene

Known as: MIXED LINEAGE LEUKEMIA, TRANSLOCATED TO, 2, MLLT2, AF-4 
This gene is involved in transcriptional regulation and translocations in the gene are associated with acute leukemia.
National Institutes of Health

Related topics

Related topics

6 relations
AF-4 proteinHomo sapiensMLL-AF4 Fusion Protein ExpressionTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
CD56-positive B cell precursor acute lymphoblastic leukemia harboring KMT2A-AFF1 rearrangement developed in a pregnant woman successfully treated with allogeneic hematopoietic cell transplantation
Although aberrant T/NK-cell antigen expression is observed approximately 10% of B cell precursor acute lymphoblastic leukemia… 
2018
2018
Controlled Disassembly and Purification of Functional Viral Subassemblies Using Asymmetrical Flow Field-Flow Fractionation (AF4)
Viruses protect their genomes by enclosing them into protein capsids that sometimes contain lipid bilayers that either reside… 
2016
2016
Association Study of an AFF1 Gene Polymorphism (rs340630) with Iranian Systemic Lupus Erythematosus Patients.
AIM To investigate whether an AFF1 polymorphism was associated with susceptibility and clinical features of SLE in Iranian… 
2014
2014
Clustering of genomic breakpoints at the MLL locus in therapy‐related acute leukemia with t(4;11)(q21;q23)
Genomic characterization of translocation breakpoints is relevant to identify possible mechanisms underlying their origin. The… 
2014
2014
Development of Molecular Marker and Variability Characterization of Aspergillus flavus Isolates of Chilies (Capsicum frutescens L.) through RAPD-PCR and Estimation of Aflatoxin B1 by Indirect…
Aflatoxin is the most potent toxic substances, these are the group of closely related mycotoxins produced by fungus i.e… 
2010
2010
Niveau de contrôle par l'apprenant de son épisode d'apprentissage hypermédia : influences sur son activité métacognitive et ses performances
Un environnement d'apprentissage hypermedia se caracterise par un haut niveau de controle de l'apprenant sur son episode d… 
2007
2007
Molecular characterization of a rare MLL-AF4 (MLL-AFF1) fusion rearrangement in infant leukemia.
2001
2001
Reduced intracellular survival of Helicobacter pylori vacA mutants in comparison with their wild-types indicates the role of VacA in pathogenesis.
The vacuolating cytotoxin VacA of Helicobacter pylori plays an important but yet unknown role in pathogenesis. We studied the… 
1999
1999
Duplicated regions of AF-4 intron 4 at t(4;11) translocation breakpoints.
1991
1991
Pheromone production and response in sterile mutants of fission yeast
SummaryGenetically heterothallic strains of various sterile mutants were assayed for residual production of the corresponding… 
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