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9-Sar-substance P sulfone

Known as: (Sar(9))SP sulfone, sarcosyl(9)-substance P sulfone, substance P, Sar(9) sulfone 
 
National Institutes of Health

Papers overview

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2008
2008
Discovery and stereoselective synthesis of the novel isochroman neurokinin-1 receptor antagonist 'CJ-17,493'.
A novel central nervous system (CNS) selective neurokinin-1 (NK(1)) receptor antagonist, (2S,3S)-3-[(1R)-6-methoxy-1-methyl-1… Expand
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2006
2006
Substance P‐induced cyclooxygenase‐2 expression in human umbilical vein endothelial cells
Substance P (SP) is a neuropeptide involved in neurogenic inflammation and an agonist for NK1, NK2, and NK3 receptors. SP induces… Expand
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2004
2004
Human isolated ileum: motor responses of the circular muscle to electrical field stimulation and exogenous neuropeptides
Summary(1) Circularly-oriented muscle strips from the human ileum responded to electrical field stimulation (1–50 Hz) with… Expand
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2004
2004
Sensory nerves, vascular endothelium and neurogenic relaxation of the guinea-pig isolated pulmonary artery
Summary1. In the presence of atropine and guanethidine (3 μmol/l each), electrical field stimulation (1–20 Hz) produced frequency… Expand
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Highly Cited
2000
Highly Cited
2000
Substance P mediates inflammatory oedema in acute pancreatitis via activation of the neurokinin‐1 receptor in rats and mice
Pancreatic oedema occurs early in the development of acute pancreatitis, and the overall extent of fluid loss correlates with… Expand
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Highly Cited
1994
Highly Cited
1994
Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P.
We evaluated the effects of nitric oxide (NO) generators and endogenous production of NO elicited by substance P (SP) in the… Expand
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1994
1994
Different Ca2+ influx pathways mediate tachykinin receptor-induced contraction in circular muscle of guinea-pig colon.
We used an electrophysiological approach (single sucrose gap) to compare the mechanism of action of selective tachykinin NK1 and… Expand
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1992
1992
Effects of selective tachykinin receptor antagonists on capsaicin- and tachykinin-induced bronchospasm in anaesthetized guinea-pigs.
Bronchospasm induced by i.v. injection of equieffective doses of acetylcholine, capsaicin or selective tachykinin receptor… Expand
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1989
1989
Effect of thiorphan on response of the guinea-pig gallbladder to tachykinins.
Tachykinins produced a concentration-related contraction of the isolated guinea-pig gallbladder, with a rank order of potency… Expand
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Highly Cited
1974
Highly Cited
1974
Location of the spike glycoproteins in the Semliki Forest virus membrane.
  • H. Garoff, K. Simons
  • Proceedings of the National Academy of Sciences…
  • 1974
    • Corpus ID: 1535775
Labeling experiments with formyl-[(35)S]-methionyl sulfone methylphosphate and crosslinking studies with dimethylsuberimidate… Expand
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