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8-hydroxyclomipramine

Known as: 5H-Dibenz(b,f)azepin-1-ol, 7-chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro- 
National Institutes of Health

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2 relations

Broader (1)

Clomipramine
analogs & derivatives

Papers overview

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2007
2007
CE of tricyclic antidepressant clomipramine and metabolites: Electromigration and wall adsorption
CE of tricyclic antidepressants clomipramine and its metabolites demethylclomipramine, didemethylclomipramine and 8… 
2005
2005
Steady-state plasma levels of clomipramine and its metabolites: Impact of the sparteine/debrisoquine oxidation polymorphism
SummaryAfter an initial placebo week, 37 depressed in-patients were treated with the fixed dose of 75 mg clomipramine b. d. A… 
2005
2005
Non-competitive inhibition of clomipramineN-demethylation by fluvoxamine
The selective serotonin reuptake inhibitor fluvoxamine interferes with the metabolism of tricyclic antidepressants. The present… 
1994
1994
Glucuronidation clearance of 8-hydroxyclomipramine in relation to sparteine and mephenytoin phenotype
Bertilsson et al. [1] reported a depressed patient who was an extremely rapid hydroxylator of both debrisoquine and nortriptyline… 
1993
1993
Clinical significance of plasma levels of clomipramine, its hydroxylated and desmethylated metabolites: prediction of clinical outcome in mood disorders using discriminant analysis of therapeutic…
1993
1993
Interindividual variations of desmethylation and hydroxylation of clomipramine in an Oriental psychiatric population.
We measured the concentrations of clomipramine and its metabolites, N-desmethylclomipramine, 8-hydroxy-N-desmethylclomipramine… 
1993
1993
[Clinical significance of plasma levels of clomipramine and its desmethylated and hydroxylated metabolites].
Concentrations of clomipramine and its metabolites, N-desmethylclomipramine (DC), 8-hydroxy-N-desmethylclomipramine (HDC) and 8… 
1982
1982
Plasma steady‐state concentrations of hydroxylated metabolites of clomipramine
Plasma clomipramine, desmethylclomipramine, 8‐hydroxyclomipramine, and 8‐hydroxydesmethylclomipramine concentrations were… 
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