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Simultaneous analysis of six antiepileptic drugs and two selected metabolites in human plasma by liquid chromatography after solid-phase extraction
Abstract A rapid and simple liquid chromatographic method with photodiode array detection was developed for the simultaneous determination of six antiepileptic drugs (oxcarbazepine, carbamazepine,Expand
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BIOANALYSIS
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HPLC analysis of the second-generation antidepressant sertraline and its main metabolite N-desmethylsertraline in human plasma.
A liquid chromatographic method with ultraviolet detection was developed for the analysis of the recent antidepressant sertraline and its main metabolite N-desmethylsertraline in human plasma. TheExpand
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Ionization constants of weak acids and bases in organic solvents.
A discussion of the influence of organic solvents on pKa values is presented. Enthalpy and entropy of ionization in organic solvents are compared with aqueous systems. The impact of the solvent onExpand
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Sensitive and selective determination of glutathione in probiotic bacteria by capillary electrophoresis–laser induced fluorescence
Glutathione (GSH) is a thiol with an important function in protecting tissue against the oxidative stress which has been related to carcinogenesis in the colon. For this reason the development ofExpand
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Analysis of the recent antipsychotic aripiprazole in human plasma by capillary electrophoresis and high-performance liquid chromatography with diode array detection.
Two methods, based on the use of capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC), respectively, were developed for the analysis of the atypical antipsychoticExpand
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Electrophoresis in fused-silica capillaries: the influence of organic solvents on the electroosmotic velocity and the .zeta. potential
3390. (44) De Le RkM J. H. Ar-h s ~ b s ~ ~ Nftrm Academic Press Inc.: New York, 1959. (45) mine, H. J. RMCW m n / s m in orgenic ”/sby, A r m & ReanangementS: Monograph 6, Eaborn, C., Chapman, N.Expand
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Determination of cationic mobilities and pKa values of 22 amino acids by capillary zone electrophoresis
The effective mobilities of the cationic forms of common amino acids – mostly proteinogenic – were determined by capillary zone electrophoresis in acidic background electrolytes at pH between 2.0 andExpand
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High-performance liquid chromatographic determination of Levetiracetam in human plasma: comparison of different sample clean-up procedures.
An accurate and precise high-performance liquid chromatographic method using diode array detection for the determination of the novel antiepileptic, Levetiracetam, has been developed. Three clean-upExpand
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Quantitation of olanzapine in tablets by HPLC, CZE, derivative spectrometry and linear voltammetry.
Four analytical methods have been developed for the quality control of pharmaceutical formulations containing the novel antipsychotic drug, olanzapine: high performance liquid chromatography (HPLC),Expand
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