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A Neural Basis for Social Cooperation
Amygdala activity related to enhanced memory for pleasant and aversive stimuli
It is shown that bilateral amygdala activity during memory encoding is correlated with enhanced episodic recognition memory for both pleasant and aversive visual stimuli relative to neutral stimuli, and that this relationship is specific to emotional stimuli.
Elevated concentrations of CSF corticotropin-releasing factor-like immunoreactivity in depressed patients.
Findings are concordant with the hypothesis that CRF hypersecretion is, at least in part, responsible for the hyperactivity of the hypothalamo-pituitary-adrenal axis characteristic of major depression.
Dissociable Neural Pathways Are Involved in the Recognition of Emotion in Static and Dynamic Facial Expressions
Comparisons of patterns of brain activity in healthy men and women during the explicit judgment of emotion intensity in static and dynamic facial expressions of anger and happiness revealed a distribution of neural activations related to the analysis of emotion messages in the nearly constant biological motion of the face and differ for angry and happy expressions.
Pharmacokinetics of methylphenidate in man, rat and monkey.
- W. Wargin, K. Patrick, G. Breese
- Biology, MedicineThe Journal of pharmacology and experimental…
- 1 August 1983
The pharmacokinetics and bioavailability of methylphenidate (MPH) and a metabolite, ritalinic acid (RA), were studied in normal adults, children with hyperactivity, monkeys and rats, suggesting substantial presystemic elimination of MPH.
Neural activity related to drug craving in cocaine addiction.
The collected findings suggest the craving-related activation of a network of limbic, paralimbic, and striatal brain regions, including structures involved in stimulus-reward association (amygdala), incentive motivation (subcallosal gyrus/nucleus accumbens), and anticipation (anterior cingulate cortex).
Neural Bases of Motivated Reasoning: An fMRI Study of Emotional Constraints on Partisan Political Judgment in the 2004 U.S. Presidential Election
- D. Westen, P. Blagov, K. Harenski, C. Kilts, S. Hamann
- Psychology, BiologyJournal of Cognitive Neuroscience
- 1 November 2006
The findings provide the first neuroimaging evidence for phenomena variously described as motivated reasoning, implicit emotion regulation, and psychological defense and suggest that motivated reasoning is qualitatively distinct from reasoning when people do not have a strong emotional stake in the conclusions reached.
The variable number of tandem repeats element in DAT1 regulates in vitro dopamine transporter density
This study identified the DAT1 VNTR as a functional polymorphism and provides an interpretive framework for its association with behavioral phenotypes.
Comparison of Dopamine Uptake in the Basolateral Amygdaloid Nucleus, Caudate‐Putamen, and Nucleus Accumbens of the Rat
Dopamine uptake in the rat brain is regionally distinct with regard to rate, affinity, and sensitivity to competitive inhibition as well as frequency dependence of dopamine efflux evoked in vivo by electrical stimulation of the medial forebrain bundle.