4-phenylbutyric acid

Known as: PHENYLBUTYRIC ACID, gamma-Phenylbutyric Acid, 4-Phenylbutanoic Acid 
 
National Institutes of Health

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2012
2012
Increasing evidence indicates that endoplasmic reticulum (ER) stress is involved in various diseases. In the human heart… (More)
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2012
2012
Evidence has shown that endoplasmic reticulum stress (ERS) is associated with the pathogenesis of cardiac hypertrophy. The aim of… (More)
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2011
2011
Exposure of cell lines endogenously expressing the thyroid hormone activating enzyme type 2 deiodinase (D2) to the chemical… (More)
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Highly Cited
2011
Highly Cited
2011
Saturated fatty acids promote lipotoxic ER (endoplasmic reticulum) stress in pancreatic β-cells in association with Type 2… (More)
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2011
2011
Trafficking through the secretory pathway is known to regulate the maturation of the APP-cleaving secretases and APP proteolysis… (More)
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Highly Cited
2010
Highly Cited
2010
Disturbance to endoplasmic reticulum (ER) homeostasis that cannot be rescued by the unfolded protein response (UPR) results in… (More)
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Highly Cited
2010
Highly Cited
2010
Prolonged endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) have been linked to apoptosis… (More)
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2009
Highly Cited
2009
Epigenetic therapy using DNA methylation inhibitors and histone deacetylase (HDAC) inhibitors has clinical promise for the… (More)
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2006
Highly Cited
2006
Expression profiling of T24 cells revealed that 17 out of 313 human miRNAs were upregulated more than 3-fold by simultaneous… (More)
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2000
Highly Cited
2000
In alpha1-AT deficiency, a misfolded but functionally active mutant alpha1-ATZ (alpha1-ATZ) molecule is retained in the… (More)
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