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Sodium phenylbutyrate

Known as: Sodium 4-phenylbutyrate, 4-Phenylbutyric Acid, Sodium Salt, sodium 4-phenylbutanoate 
The sodium salt of phenylbutyrate, a derivative of the short-chain fatty acid butyrate, with potential antineoplastic activity. Phenylbutyrate… 
National Institutes of Health

Related topics

Related topics

16 relations

Broader (2)

4-phenylbutyric acidphenylbutyrate
Anemia, Sickle CellCystic FibrosisDNA Strand BreakDNA Synthesis Inhibition

Narrower (1)

Buphenyl

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Direct acting inhibitors of ammoniagenesis: a role in post-TIPS encephalopathy?
Review
2008
Review
2008
Fetal globin stimulant therapies in the beta-hemoglobinopathies: principles and current potential.
For the majority of children with beta- hemoglobinopathies and -thalassemias who do not have a transplant donor, survival is… 
2008
2008
Growth inhibition and gene induction in human hepatocellular carcinoma cell exposed to sodium 4-phenylbutanoate.
BACKGROUND Sodium 4-phenylbutanoate (NaPB) can induce cellular differentiation and cell cycle arrest. However, its potential… 
Review
2007
Review
2007
[Urea cycle disorders in adult patients].
2007
2007
Stability of extemporaneously prepared sodium phenylbutyrate oral suspensions.
PURPOSE In an effort to minimize barriers to compliance and adherence and to improve the accuracy of dosage measurement, sugar… 
2001
2001
Sodium phenylbutyrate induces apoptosis in human retinoblastoma Y79 cells: the effect of combined treatment with the topoisomerase I-inhibitor topotecan.
Our results demonstrate that sodium phenylbutyrate, a compound with a low degree of toxicity, exerted a cytotoxic effect on human… 
2000
2000
A novel approach for nasopharyngeal carcinoma treatment uses phenylbutyrate as a protein kinase C modulator: implications for radiosensitization and EBV-targeted therapy.
Sodium phenylbutyrate (NaPB) represent a new non-toxic class of compounds with antiproliferative activities to different tumors… 
Review
2000
Review
2000
Focus on "Sodium 4-phenylbutyrate downregulates Hsc70: implications for intracellular trafficking of DeltaF508-CFTR".
  • N. Bradbury
  • American Journal of Physiology - Cell Physiology
  • 2000
  • Corpus ID: 34895582
the ability of newly synthesized proteins, particularly oligomeric or multidomain proteins, to fold into unique, three… 
1999
1999
PBA increases CFTR expression but at high doses inhibits Cl(-) secretion in Calu-3 airway epithelial cells.
Sodium 4-phenylbutyrate (PBA), a short-chain fatty acid, has been approved to treat patients with urea cycle enzyme deficiencies… 
1998
1998
Cytotoxic effects of sodium phenylbutyrate on human neuroblastoma cell lines.
Sodium phenylbutyrate (NaPB) is used in urea cycle disorders. We screened 6 neuroblastoma cell lines for in vitro potency of NaPB… 
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