Sodium phenylbutyrate

Known as: Sodium 4-phenylbutyrate, 4-Phenylbutyric Acid, Sodium Salt, sodium 4-phenylbutanoate 
The sodium salt of phenylbutyrate, a derivative of the short-chain fatty acid butyrate, with potential antineoplastic activity. Phenylbutyrate… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
OBJECTIVE Chronically elevated free fatty acids contribute to insulin resistance and pancreatic β-cell failure. Among numerous… (More)
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Highly Cited
2009
Highly Cited
2009
Chromatin modification through histone acetylation is a molecular pathway involved in the regulation of transcription underlying… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE To evaluate the effect of chemical chaperones on the trafficking of secretion-incompetent primary open-angle glaucoma… (More)
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Highly Cited
2005
Highly Cited
2005
Multiple molecular defects trigger cell death in amyotrophic lateral sclerosis (ALS). Among these, altered transcriptional… (More)
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Highly Cited
2005
Highly Cited
2005
Spinal muscular atrophy (SMA) is caused by insufficient levels of survival motor neuron (SMN) protein. Recently, we found that… (More)
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Highly Cited
2004
Highly Cited
2004
Sodium 4-phenylbutyrate (4-PBA) is a low molecular weight fatty acid that has been used for treatment of urea cycle disorders in… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE Sodium phenylbutyrate (PB) demonstrates potent differentiating capacity in multiple hematopoietic and solid tumor cell… (More)
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Highly Cited
2000
Highly Cited
2000
The most common mutation of the cystic fibrosis transmembrane conductance regulator (CFTR), DeltaF508, is a trafficking mutant… (More)
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Highly Cited
1998
Highly Cited
1998
Sodium 4-phenylbutyrate (Buphenyl, 4PBA) is a new FDA approved drug for management of urea cycle disorders. We have previously… (More)
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Highly Cited
1997
Highly Cited
1997
The most common cystic fibrosis transmembrane conductance regulator mutation, delta F508-CFTR, is a partially functional chloride… (More)
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