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4-hydroxybutyric acid

Known as: GHB, Gamma Hydroxybutyric Acid, oxy-n-butyric acid 
A naturally occurring short-chain fatty acid, and immediate precursor of gamma amino butyric acid (GABA) with neuromodulatory and anesthetic… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Hydroxy AcidsHydroxybutyrates

Narrower (2)

Sodium Oxybategamma hydroxybutyrate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
The epidemiology of GHB and ketamine use in an Australian household survey.
Review
2005
Review
2005
Gamma hydroxy butyrate abuse and dependency
The recreational use of gamma hydroxy butyrate (GHB) has gained popularity over the last decade. GHB was initially sold as a safe… 
Highly Cited
2003
Highly Cited
2003
Modular Organization of the Carboxyl-Terminal, Globular Head Region of Human C1q A, B, and C Chains1
The first step in the activation of the classical complement pathway, by immune complexes, involves the binding of the globular… 
Highly Cited
2003
Highly Cited
2003
Determination of endogenous levels of GHB in human hair. Are there possibilities for the identification of GHB administration through hair analysis in cases of drug-facilitated sexual assault?
We have developed a GC-MS-MS assay for GHB in human hair. Five milligrams of washed hair were hydrolyzed by 1M or 0.01M NaOH… 
Highly Cited
2003
Highly Cited
2003
Cloning and characterization of a rat brain receptor that binds the endogenous neuromodulator γ‐hydroxybutyrate
γ‐Hydroxybutyrate (GHB) is an endogenous neuromodulator with therapeutical applications in anesthesia, sleep disorders, and drug… 
Highly Cited
1999
Highly Cited
1999
Gamma-hydroxybutyrate is a weak agonist at recombinant GABA(B) receptors.
Gamma-hydroxybutyrate (GHB) is a neuromodulator with high affinity binding sites in the mammalian brain. However, the receptor… 
Highly Cited
1996
Highly Cited
1996
Mesolimbic dopaminergic reduction outlasts ethanol withdrawal syndrome: Evidence of protracted abstinence
Highly Cited
1978
Highly Cited
1978
Gabaergic processes involved in the control of dopamine release from nigrostriatal dopaminergic neurons in the cat.
Highly Cited
1972
Highly Cited
1972
Effect of gamma-hydroxybutyrate on dopamine and dopamine metabolites in the rat striatum.
Highly Cited
1963
Highly Cited
1963
Studies on the electron transfer system. LI. Isolation and characterization of the D-(--)-beta-hydroxybutyric apodehydrogenase from beef heart mitochondria.
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