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Sodium Oxybate

Known as: Sodium Oxybutyrate, Sodium Oxybate [Chemical/Ingredient], 4-Hydroxybutyrate Sodium 
The sodium salt of 4-hydroxybutyric acid. It is used for both induction and maintenance of ANESTHESIA.
National Institutes of Health

Related topics

Related topics

21 relations

Broader (7)

4-hydroxybutyric acidAdjuvants, AnesthesiaAnestheticsAnesthetics, Intravenous

Narrower (5)

6-tuliposide ASomsanitXyremtuliposide A
BarbituratesCataplexyIn Bloodagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Efficacy and safety of sodium oxybate in alcohol‐dependent patients with a very high drinking risk level
Medication development for alcohol relapse prevention or reduction of consumption is highly challenging due to methodological… 
Review
2018
Review
2018
Medication induced sleepwalking: A systematic review.
Review
2015
Review
2015
Alcohol Withdrawal Syndrome: Benzodiazepines and Beyond.
Alcohol dependence is an increasing and pervasive problem. Alcohol withdrawal symptoms are a part of alcohol dependence syndrome… 
Review
2013
Review
2013
Mazindol in narcolepsy and idiopathic and symptomatic hypersomnia refractory to stimulants: a long-term chart review.
Highly Cited
2009
Highly Cited
2009
Sleepiness in Parkinson's disease.
Review
2008
Review
2008
Narcolepsy in children: a single-center clinical experience.
Review
2006
Review
2006
Off-label treatment of severe childhood narcolepsy-cataplexy with sodium oxybate.
STUDY OBJECTIVES To evaluate the efficacy and side-effect profile of off-label sodium oxybate (gamma hydroxy butyrate) therapy in… 
Highly Cited
1979
Highly Cited
1979
Dose-dependent pharmacokinetics and hypnotic effects of sodium gamma-hydroxybutyrate in the rat.
The pharmacokinetics of sodium-gamma-hydroxybutyrate (NaGHB) have been examined as functions of dose and route of administration… 
Highly Cited
1978
Highly Cited
1978
Improved pharmacological activity via pro-drug modification: comparative pharmacokinetics of sodium gamma-hydroxybutyrate and gamma-butyrolactone.
Although gamma-butyrolactone (GBL) rapidly converts to gamma-hydroxybutyrate (GHB) in vivo, the lactone gave significantly more… 
Highly Cited
1960
Highly Cited
1960
[Summary of an experimental and clinical study on a metabolic substrate with inhibitory central action: sodium 4-hydroxybutyrate].
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