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Caffeinated energy drinks--a growing problem.
Several studies suggest that energy drinks may serve as a gateway to other forms of drug dependence, and regulatory implications concerning labeling and advertising, and the clinical implications for children and adolescents are discussed. Expand
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial
High-dose psilocybin produced large decreases in clinician- and self-rated measures of depressed mood and anxiety, along with increases in quality of life, life meaning, and optimism, and decreases in death anxiety. Expand
Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness
Assessment of the effect of psilocybin on changes in the five broad domains of personality – Neuroticism, Extroversion, Openness, Agreeableness, and Conscientiousness found significant increases in Openness following a high-dose p silocybin session. Expand
Psilocybin occasioned mystical-type experiences: immediate and persisting dose-related effects
Under supportive conditions, 20 and 30 mg/70 kg psilocybin occasioned mystical-type experiences having persisting positive effects on attitudes, mood, and behavior. Expand
Increased Alcohol Consumption, Nonmedical Prescription Drug Use, and Illicit Drug Use Are Associated With Energy Drink Consumption Among College Students
A substantial and rapidly growing proportion of college students use energy drinks, and energy drink users tend to have greater involvement in alcohol and other drug use and higher levels of sensation seeking, relative to nonusers of energy drinks. Expand
Energy drink consumption and increased risk for alcohol dependence.
BACKGROUND Energy drinks are highly caffeinated beverages that are increasingly consumed by young adults. Prior research has established associations between energy drink use and heavier drinking andExpand
Validation of the revised Mystical Experience Questionnaire in experimental sessions with psilocybin
A method to score a “complete mystical experience” that was used in previous versions of the mystical experience questionnaire is validated in the MEQ30, and a stand-alone version of theMEQ30 is provided for use in future research. Expand
A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and associated features
The caffeine-withdrawal syndrome has been well characterized and there is sufficient empirical evidence to warrant inclusion of caffeine withdrawal as a disorder in the DSM and revision of diagnostic criteria in the ICD. Expand
Principles of drug abuse liability assessment in laboratory animals.
The rationale for use of preclinical assessments of abuse liability in laboratory animals is described, and "cross-cutting" methodological issues that apply to behavioral evaluations intended to contribute to an abuse liability evaluation package are discussed. Expand
Relative abuse liability of hypnotic drugs: a conceptual framework and algorithm for differentiating among compounds.
Concern about recreational abuse, inappropriate long-term use, or adverse effects should not deter physicians from prescribing hypnotics when clinically indicated, according to the primary clinical implication. Expand