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Barbiturates

Known as: Barbiturate, Barbiturates [Chemical/Ingredient] 
A class of drugs characterized as central nervous system (CNS) depressants. Barbiturate compounds bind to the gamma amino butyric acid (GABA)-A… 
National Institutes of Health

Related topics

Related topics

49 relations

Narrower (27)

1,3-dimethylbarbituric acid1-methyl barbituric acid2-hydroxylamino-5-ethyl-5-propylbarbituric acid5-allyl-5-isopropyl-1-methylbarbituric acid
Anesthetics, IntravenousBARBITURATES TESTED FOR:PRID:PT:UR:NOM:SCREENBarbiturates:MCnc:Pt:Meconium:QnBarbiturates:MCnc:Pt:Urine:Qn:Confirm

Broader (5)

Central Nervous System DepressantsGeneral anesthetic drugsPharmaceutical PreparationsPyrimidines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2002
Review
2002
Anxiety over GABA(A) receptor structure relieved by AChBP.
Highly Cited
1998
Highly Cited
1998
A new genetic defect in human CYP2C19: mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin.
The 4'-hydroxylation of the S-enantiomer of the anticonvulsant drug mephenytoin exhibits a genetic polymorphism in humans. This… 
Review
1991
Review
1991
GABAA receptor subtypes: from pharmacology to molecular biology
GABAA receptors are GABA (γ‐amino‐butyric acid)‐gated chloride channels, which are major mediators of neuronal inhibition in the… 
Highly Cited
1990
Highly Cited
1990
Changing patterns of c-fos induction in spinal neurons following thermal cutaneous stimulation in the rat
Review
1981
Review
1981
Mechanism of action of barbiturates.
Despite the widespread use of barbiturates and their clear potential for abuse, little is known of their neurochemical mechanisms… 
Highly Cited
1978
Highly Cited
1978
Benzodiasepine and neurotransmitter receptor binding in rat brain after chronic administration of diazepam or phenobarbital
Review
1975
Review
1975
Drug-induced systemic lupus erythematosus: a critical review.
Highly Cited
1974
Highly Cited
1974
Thyrotropin releasing hormone: Antagonism of pentobarbital in rodents
Highly Cited
1972
Highly Cited
1972
Chapter 6 – Long-term Intravenous Infusion
Highly Cited
1968
Highly Cited
1968
Re-analysis of the antidromic cortical response. II. On the contribution of cell discharge and PSPs to the evoked potentials.
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