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Barbiturates

Known as: Barbiturate, Barbiturates [Chemical/Ingredient] 
A class of drugs characterized as central nervous system (CNS) depressants. Barbiturate compounds bind to the gamma amino butyric acid (GABA)-A… 
National Institutes of Health

Related topics

Related topics

49 relations

Narrower (27)

1,3-dimethylbarbituric acid1-methyl barbituric acid2-hydroxylamino-5-ethyl-5-propylbarbituric acid5-allyl-5-isopropyl-1-methylbarbituric acid
Anesthetics, IntravenousBARBITURATES TESTED FOR:PRID:PT:UR:NOM:SCREENBarbiturates:MCnc:Pt:Meconium:QnBarbiturates:MCnc:Pt:Urine:Qn:Confirm

Broader (5)

Central Nervous System DepressantsGeneral anesthetic drugsPharmaceutical PreparationsPyrimidines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1999
Review
1999
Are we dependent upon coffee and caffeine? A review on human and animal data
Highly Cited
1994
Highly Cited
1994
Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily.
Highly Cited
1990
Highly Cited
1990
The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor
Review
1988
Review
1988
Aneurysms of the basilar artery treated with circulatory arrest, hypothermia, and barbiturate cerebral protection.
Complete circulatory arrest, deep hypothermia, and barbiturate cerebral protection are efficacious adjuncts in the surgical… 
Highly Cited
1986
Highly Cited
1986
Characterization of a catalytically self-sufficient 119,000-dalton cytochrome P-450 monooxygenase induced by barbiturates in Bacillus megaterium.
Highly Cited
1975
Highly Cited
1975
Prolongation of hippocampal inhibitory postsynaptic potentials by barbiturates
IT is well documented that barbiturates dramatically prolong presynaptic inhibition1–4. Their effect on postsynaptic inhibition… 
Highly Cited
1969
Highly Cited
1969
Effect of barbiturates on ‘quantal’ synaptic transmission in spinal motoneurones
1. Monosynaptic excitatory post‐synaptic potentials (EPSPs) produced in triceps surae motoneurones of the cat by stimulation of… 
Highly Cited
1966
Highly Cited
1966
Physiological properties of unmyelinated fiber projection to the spinal cord.
Highly Cited
1950
Highly Cited
1950
A 24-hour periodicity in the "LH-release apparatus" of female rats, disclosed by barbiturate sedation.
UNTIL very recently the importance of the nervous system in evoking the ovulatory discharge of gonadotrophin has been recognized… 
Highly Cited
1949
Highly Cited
1949
Effect upon the EEG of acute injury to the brain stem activating system.
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