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1-hydroxymethylpyrene

Known as: 1-hydroxymethyl-pyren 
National Institutes of Health

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Broader (1)

Pyrenes

Papers overview

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2014
2014
Human CYP2E1-dependent and human sulfotransferase 1A1-modulated induction of micronuclei by benzene and its hydroxylated metabolites in Chinese hamster V79-derived cells.
2004
2004
Kohlenwasserstoffe in der Umgebung des Menschen
Weizen, Gerste und Roggen sind je nach Standort verschieden stark mit polycyclischen Kohlenwasserstoffen verunreinigt, von denen… 
Review
1998
Review
1998
Bioactivation of benzylic and allylic alcohols via sulfo-conjugation.
1998
1998
Expression of human estrogen sulfotransferase in Salmonella typhimurium: differences between hHST and hEST in the enantioselective activation of 1-hydroxyethylpyrene to a mutagen.
1995
1995
Activation of benzylic alcohols to mutagens by rat and human sulfotransferases expressed in Escherichia coli.
1995
1995
Quantitative analysis of multiple phenotype enzyme-altered foci in rat hepatocarcinogenesis experiments: the multipath/multistage model.
The promotional effect of phenobarbital and 1-hydroxymethyl-pyren on enzyme altered lesions in the rat liver were quantified… 
1994
1994
Activation of promutagens by endogenous and heterologous sulfotransferases expressed in continuous cell cultures.
Review
1991
Review
1991
Activation of 1-hydroxymethylpyrene to an electrophilic and mutagenic metabolite by rat hepatic sulfotransferase activity.
Hydroxylation of meso-methyl groups with subsequent formation of reactive benzylic esters bearing a good leaving group (e.g… 
Highly Cited
1990
Highly Cited
1990
Metabolic activation of 9-hydroxymethyl-10-methylanthracene and 1-hydroxymethylpyrene to electrophilic, mutagenic and tumorigenic sulfuric acid esters by rat hepatic sulfotransferase activity.
Our previous studies on 7-hydroxymethyl-12-methylbenz[a]anthracene and 6-hydroxymethylbenzo[a]pyrene showed that cytosolic… 
Highly Cited
1986
Highly Cited
1986
Mutagenicity of benzylic acetates, sulfates and bromides of polycyclic aromatic hydrocarbons.
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