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1-hydroxy-3-methylcholanthrene

Known as: 1,2-dihydro-3-methylbenz(j)aceanthrylen- 1-ol 
National Institutes of Health

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2 relations

Broader (1)

Methylcholanthrene
analogs & derivatives

Papers overview

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2006
2006
Metabolism and DNA Binding of 3-Methylcholanthrene1
Rat liver microsomes metabolize 3-methylcholanthrene (3MC) to oxygenated forms which alkylate DNA. Analysis of the DNA-bound… 
1990
1990
1-Hydroxy- and 2-hydroxy-3-methylcholanthrene: regioselective and stereoselective formations in the metabolism of 3-methylcholanthrene and enantioselective disposition in rat liver microsomes.
Absolute configurations of enantiomeric 1-hydroxy-3-methylcholanthrene (1-OH-3MC) and 2-hydroxy-3-methyl-cholanthrene (2-OH-3MC… 
1990
1990
Enantioselective aliphatic hydroxylations of racemic 1-hydroxy-3-methylcholanthrene by rat liver microsomes.
Enantiomeric pairs of 1-hydroxy-3-hydroxymethylcholanthrene (1-OH-3-OHMC), 3-methylcholanthrene (3MC) trans- and cis-1,2-diols… 
1990
1990
9,10-Dihydroxy-9,10-dihydro-3-methylcholanthrene-2-one: a principal metabolite of the potent carcinogen 3-methylcholanthrene-2-one by rat liver microsomes.
A principal metabolite, formed in the metabolism of the potent carcinogen 3-methylcholanthrene-2-one (3MC-2-one) by liver… 
1987
1987
Purification and photoaffinity labelling of a rat cytosolic binding protein specific for 3-methylcholanthrene.
Rat hepatic cytosolic proteins which sediment at 4-5 S on sucrose gradients exhibit high-affinity saturable binding for the… 
1984
1984
Direct enantiomeric resolution of cyclic alcohol derivatives of polycyclic aromatic hydrocarbons by chiral stationary phase high-performance liquid chromatography.
1984
1984
The metabolism of 1-hydroxy- and 2-hydroxy-3-methylcholanthrene by liver microsomes: effect of enzyme inducing agents.
1979
1979
Tumorigenic activity of 3-methylcholanthrene metabolites on mouse skin and in newborn mice.
3-Methylcholanthrene and eight of its metabolites were tested for tumorigenic activity in two tumor models. In the tumorigenicity… 
1978
1978
Carcinogenicity and metabolic profiles of 3-methylcholanthrene oxygenated derivatives at the 1 and 2 positions.
1978
1978
9,10-Dihydrodiols of 1-hydroxy-3-methylcholanthrene: potential proximate carcinogens derived from 3-methylcholanthrene
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