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Methylcholanthrene

Known as: Benz(j)aceanthrylene, 1,2-dihydro-3-methyl-, Methylcholanthrene [Chemical/Ingredient] 
A carcinogen that is often used in experimental cancer studies.
National Institutes of Health

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Related topics

17 relations

Narrower (11)

1-hydroxy-3-methylcholanthrene1-sulfooxy-3-methylcholanthrene2-hydroxy-3-methylcholanthrene20-Methylcholanthrene
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Broader (2)

CarcinogensPolycyclic Hydrocarbons
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
γδ T Cells Provide an Early Source of Interferon γ in Tumor Immunity
Interferon (IFN)-γ is necessary for tumor immunity, however, its initial cellular source is unknown. Because γδ T cells primarily… Expand
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Highly Cited
1988
Highly Cited
1988
Toxic effect of tumor necrosis factor on tumor vasculature in mice.
Stereoscopic observation via an implanted sight glass in mice bearing transplanted methylcholanthrene-induced A-cells showed… Expand
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Highly Cited
1976
Highly Cited
1976
Regualtion of the immune response to tumor antigens. I. Immunosuppressor cells in tumor-bearing hosts.
A/Jax mice were rendered immune to the syngeneic and transplantable methylcholanthrene-induced Sarcoma 1509a by the surgical… Expand
Highly Cited
1975
Highly Cited
1975
Effect of tumour necrosis factor on cultured human melanoma cells
CARSWELL et al.1 described a tumour necrosis factor (TNF) in the sera of mice sensitised with BCG and injected with endotoxin… Expand
Highly Cited
1969
Highly Cited
1969
Studies on cellular immunity and its serum‐mediated inhibition in moloney‐virus‐induced mouse sarcomas
A colony‐inhibition technique was used to demonstrate lymph‐node cell (LNC) mediated immune reactions against tumor‐specific… Expand
Highly Cited
1968
Highly Cited
1968
In vitro studies of immune reactions against autochthonous and syngeneic mouse tumors induced by methylcholanthrene and plastic discs
A colony inhibition (CI) technique was used to demonstrate lymph node cell (LNC) and serum‐mediated immune reactions against… Expand
Highly Cited
1964
Highly Cited
1964
Effect on Tumour Growth in Syngeneic Recipients of Antibodies Against Tumour-Specific Antigens in Methylcholanthrene-Induced Mouse Sarcomas
Effect on Tumour Growth in Syngeneic Recipients of Antibodies Against Tumour-Specific Antigens in Methylcholanthrene-Induced… Expand
Highly Cited
1960
Highly Cited
1960
Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host.
Summary Host resistance against methylcholanthrene (MC)-induced sarcomas, demonstrated by previous authors after transplantation… Expand
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Highly Cited
1951
Highly Cited
1951
White Thromboembolism in the Hamster Cheek Pouch after Trauma, Infection and Neoplasia
White thrombosis and embolism were investigated by cinephotomicroscopy in the transillumined cheek pouch of the hamster in an… Expand
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Highly Cited
1941
Highly Cited
1941
Experimental Brain Tumors. I. Tumors Produced with Methylcholanthrene
Efforts to produce intracranial neoplasia by various chemical carcinogens have been attended with scant success prior to the work… Expand
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