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1-Phosphatidylinositol 3-Kinase

Known as: Type I Phosphatidylinositol Kinase, Phosphatidylinositol 3-Kinase [Chemical/Ingredient], Phosphatidylinositol-3-Kinase 
An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling is one of the most important… Expand
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Review
2019
Review
2019
Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common age-related neurodegenerative disorders, affecting… Expand
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Review
2019
Review
2019
In addition to protecting body from infections and diseases, the immune system produces auto-antibodies that can cause complex… Expand
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Review
2019
Review
2019
Disruption of Akt and Erk-mediated signal transduction significantly contributes in the pathogenesis of various neurodegenerative… Expand
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Review
2019
Review
2019
Abstract Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) are heterogeneous regarding site of origin, biological… Expand
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Review
2019
Review
2019
ABSTRACT Mitophagy is a vital form of autophagy for selective removal of dysfunctional or redundant mitochondria. Accumulating… Expand
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Review
2018
Review
2018
Metallothioneins (MTs) are small cysteine-rich proteins that play important roles in metal homeostasis and protection against… Expand
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Review
2018
Review
2018
Most tumor cells reprogram their glucose metabolism as a result of mutations in oncogenes and tumor suppressors, leading to the… Expand
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Highly Cited
2002
Highly Cited
2002
Recent studies have demonstrated that fatty acids induce insulin resistance in skeletal muscle by blocking insulin activation of… Expand
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Highly Cited
1994
Highly Cited
1994
Phosphatidylinositol (PtdIns) 3-kinase is an enzyme implicated in growth factor signal transduction by associating with receptor… Expand
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