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Phosphoinositide-3-Kinase, Catalytic, Beta Polypeptide

Known as: PIK3CB, PI3KBeta, PI3-Kinase p110 Subunit Beta 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (1070 aa, ~123 kDa) is encoded by the human PIK3CB gene. This protein… 
National Institutes of Health

Related topics

Related topics

23 relations
1-Phosphatidylinositol 3-Kinase1-phosphatidylinositol-3-kinase activityApoptosisB Cell Receptor Signaling Pathway

Papers overview

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2015
2015
Upregulation of Nicotinic Acetylcholine Receptor alph4+beta2 through a Ligand-Independent PI3Kbeta Mechanism That Is Enhanced by TNFalpha and the Jak2/p38Mapk Pathways
High affinity nicotine-binding sites in the mammalian brain are neuronal nicotinic acetylcholine receptors (nAChR) assembled from… 
2015
2015
TNFR1 Regulates Ovarian Cancer Cell Tumorigenicity Through PIK3CB-p110Beta.
Studies have shown that TNFR1 is a key factor in the tumor microenvironment that is dependent on the TNF-α-initiated cascade for… 
2010
2010
115 Discovery and characterization of PI3Kbeta isoform-selective inhibitors
2008
2008
Overlapping and distinct roles for PI3Kbeta and gamma isoforms in S1P-induced migration of human and mouse endothelial cells.
AIMS Sphingosine-1-phosphate (S1P), a key regulator of vascular homeostasis and angiogenesis, promotes endothelial cell migration… 
2008
2008
Activity of the p110-alpha subunit of phosphatidylinositol-3-kinase is required for activation of epithelial sodium transport.
The pathways implicated in the control of epithelial Na(+) channel (ENaC)-dependent Na(+) transport in renal collecting duct… 
Highly Cited
2001
Highly Cited
2001
Phosphoinositide 3-kinase isoforms selectively couple receptors to vascular L-type Ca(2+) channels.
Heterodimeric class I phosphoinositide 3-kinase (PI3K) has been shown to be involved in the stimulation of voltage-gated Ca(2… 
2001
2001
Phosphoinositide 3-Kinase Isoforms Selectively Couple Receptors to Vascular L-Type Ca Channels
Heterodimeric class I phosphoinositide 3-kinase (PI3K) has been shown to be involved in the stimulation of voltage-gated Ca 21… 
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