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1-(3-chlorophenyl)piperazine

Known as: 3-chlorophenylpiperazine, 1-(m-chlorophenyl)piperazine, m chlorophenylpiperazine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2017
02419812017

Related topics

Related topics

4 relations

Narrower (1)

1-(3-chlorophenyl)piperazine dihydrochloride

Broader (3)

PiperazinesSerotonin Agonistspiperazine

Related mentions per year

Related mentions per year

1945-2018
19401960198020002020
1-(3-chlorophenyl)piperazine
piperazine
Serotonin Agonists
Piperazines
1-(3-chlorophenyl)piperazine dihydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Investigation of the first deaths in the United Kingdom involving the detection and quantitation of the piperazines BZP and 3-TFMPP.
Piperazines such as 1-benzylpiperazine (BZP), 1-(3-trifluromethylphenyl)piperazine (3-TFMPP), and 1-(3-chlorophenyl)piperazine (3… (More)
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2007
2007
Proof of a 1-(3-chlorophenyl)piperazine (mCPP) intake: use as adulterant of cocaine resulting in drug-drug interactions?
Since 2005, increasing numbers of seizures of the designer drug of abuse 1-(3-chlorophenyl)piperazine (mCPP) have been reported… (More)
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2003
2003
Piperazine-derived designer drug 1-(3-chlorophenyl)piperazine (mCPP): GC-MS studies on its metabolism and its toxicological detection in rat urine including analytical differentiation from its…
Studies on the metabolism and the toxicological analysis of the piperazine-derived designer drug 1-(3-chlorophenyl)piperazine… (More)
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Highly Cited
1997
Highly Cited
1997
RS-102221: a novel high affinity and selective, 5-HT2C receptor antagonist.
The 5-HT2C receptor is one of three closely related receptor subtypes in the 5-HT2 receptor family. 5-HT2A and 5-HT2B selective… (More)
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1996
1996
Effects of the 5-HT2C/2B receptor agonist 1-(3-chlorophenyl) piperazine on plasma glucose levels of rats.
Acute administration of the 5-HT2C/2B receptor agonist 1-(3-chlorophenyl)piperazine (mCPP, 5-10 mg/kg i.p.) induced hyperglycemia… (More)
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Highly Cited
1995
Highly Cited
1995
(1-(2,5-dimethoxy-4 iodophenyl)-2-aminopropane)-induced head-twitches in the rat are mediated by 5-hydroxytryptamine (5-HT) 2A receptors: modulation by novel 5-HT2A/2C antagonists, D1 antagonists and…
In this study, the involvement of serotonergic and dopaminergic receptors in the modulation of the head-twitch (HTW) response to… (More)
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Highly Cited
1989
Highly Cited
1989
Anxiogenic-like effects of mCPP and TFMPP in animal models are opposed by 5-HT1C receptor antagonists.
1-(3-chlorophenyl)piperazine (mCPP) and 1-[3-(trifluoromethyl)phenyl]piperazine (TFMPP) (0.1-1.0 mg/kg) reduce total interaction… (More)
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Highly Cited
1988
Highly Cited
1988
Evidence that mCPP may have behavioural effects mediated by central 5-HT1C receptors.
1. The effects of 1-(3-chlorophenyl)piperazine (mCPP) and 1-[3-(trifluoromethyl)phenyl] piperazine (TFMPP) on activity of rats in… (More)
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Highly Cited
1988
Highly Cited
1988
Evidence that hypophagia induced bymCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors
Male Sprague-Dawley rats deprived of food for 18 h were injected with the 5-HT agonists RU 24969, 1-(3-chlorophenyl)piperazine… (More)
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1981
1981
Enhancement of responsiveness of the central serotonergic system and serotonin-2 receptor density in rat frontal cortex by electroconvulsive treatment.
The effect of a series of 10 electroconvulsive shocks (ECS) on the hyperthermic response of heat-adapted rats to a serotonergic… (More)
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