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Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
It is demonstrated that voluntary exercise is sufficient for enhanced neurogenesis in the adult mouse dentate gyrus, in amounts similar to enrichment conditions.
Functional neurogenesis in the adult hippocampus
It is reported that newly generated cells in the adult mouse hippocampus have neuronal morphology and can display passive membrane properties, action potentials and functional synaptic inputs similar to those found in mature dentate granule cells.
Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male sprague–dawley rats in vivo
Neural consequences of enviromental enrichment
This article focuses on the neuronal changes that occur in response to complex stimulation by an enriched environment and emphasizes the behavioural and neurobiological consequences of specific elements of enrichment, especially exercise and learning.
Synapse formation on neurons born in the adult hippocampus
It is reported that new neurons born in the adult mouse hippocampus were contacted by axosomatic, axodendritic and axospinous synapses, and dendritic spines primarily synapsed on multiple-synapse boutons, suggesting that initial contacts were preferentially made with preexisting boutons already involved in a synapse.
Bridging animal and human models of exercise-induced brain plasticity
Neurogenesis and Exercise: Past and Future Directions
- H. Praag
- Biology, PsychologyNeuroMolecular Medicine
- 20 February 2008
An overview of research pertaining to exercise-induced cell genesis, its possible relevance to memory function and the cellular mechanisms that may be involved in this process is given.
Adult brain neurogenesis and psychiatry: a novel theory of depression
It is hypothesized that the waning and waxing of neurogenesis in the hippocampal formation are important causal factors, respectively, in the precipitation of, and recovery from, episodes of clinical depression.
Exercise and the brain: something to chew on
- H. Praag
- BiologyTrends in Neurosciences
- 1 May 2009