vesnarinone

Known as: 3,4-dihydro-6-(4-(3,4-dimethoxybenzoyl)-1-piperazinyl)-2-1H-quinolinone, vesnarinone [Chemical/Ingredient], 3,4-Dihydro-6-(4-(3,4-dimethoxybenzoyl)-1-pip- erazinyl)- 2(1H)-quinolinone 
A cardiotonic quinolinone derivative, that suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an inhibitor of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2017
0102019862017

Papers overview

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2009
2009
We have demonstrated that the stromal cell-derived factor-1 (SDF-1; CXCL12)/CXCR4 system is involved in the establishment of… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Previous reports have shown that elevated circulating levels of cytokines and/or cytokine receptors predict adverse… (More)
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2001
2001
Vesnarinone, a cardiotonic agent, blocks I(Kr) and, unlike other I(Kr) blockers, produces a frequency-dependent prolongation of… (More)
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2000
2000
Vesnarinone, a synthetic quinolinone derivative used in the treatment of cardiac failure, exhibits immunomodulatory, anti… (More)
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1999
1999
OBJECTIVE The systemic inflammatory response is an important cause of organ dysfunction. The present study tested the hypothesis… (More)
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1998
1998
We undertook the present study to clarify the molecular mechanism of the effect of a new anti-cancer drug, vesnarinone, on a… (More)
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1995
1995
Vesnarinone is a new and novel inotropic drug that has unique and complex mechanisms of action. It inhibits phosphodiesterase… (More)
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1994
1994
Vesnarinone is an important new drug that significantly decreases mortality rates in severe congestive heart failure; however… (More)
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1994
1994
BACKGROUND Vesnarinone, a quinolinone derivative, is a recently synthesized positive inotropic agent that has been shown to… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND Inotropic therapy, other than with digitalis glycosides, has had limited success in patients with chronic congestive… (More)
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