Skip to search formSkip to main contentSkip to account menu

vesnarinone

Known as: 3,4-dihydro-6-(4-(3,4-dimethoxybenzoyl)-1-piperazinyl)-2-1H-quinolinone, vesnarinone [Chemical/Ingredient], 3,4-Dihydro-6-(4-(3,4-dimethoxybenzoyl)-1-pip- erazinyl)- 2(1H)-quinolinone 
A cardiotonic quinolinone derivative, that suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an inhibitor of… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (6)

Antineoplastic AgentsAntiviral AgentsCardiotonic AgentsImmunologic Adjuvants

Narrower (3)

ArkinArkin-ZOPC 8212

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Novel quinolinone–pyrazoline hybrids: synthesis and evaluation of antioxidant and lipoxygenase inhibitory activity
The present project deals with the investigation of structure–activity relationship of several quinolinone–chalcone and… 
2009
2009
Tyrokeradines A and B, new bromotyrosine alkaloids with an imidazolyl-quinolinone moiety from a verongid sponge.
2004
2004
Optimization of the indolyl quinolinone class of KDR (VEGFR-2) kinase inhibitors: effects of 5-amido- and 5-sulphonamido-indolyl groups on pharmacokinetics and hERG binding.
2004
2004
3-Thio-quinolinone maxi-K openers for the treatment of erectile dysfunction.
Review
2003
Review
2003
Role of nonglycosidic inotropic agents: indications, ethics, and limitations.
Highly Cited
2001
Highly Cited
2001
Novel bromotyrosine alkaloids: inhibitors of mycothiol S-conjugate amidase.
[structure: see text] The novel alkaloids 1 and 4 were isolated from an Australian non-verongid sponge, Oceanapia sp. Compound 1… 
Highly Cited
1998
Highly Cited
1998
Induction of TSC-22 by treatment with a new anti-cancer drug, vesnarinone, in a human salivary gland cancer cell.
We undertook the present study to clarify the molecular mechanism of the effect of a new anti-cancer drug, vesnarinone, on a… 
1994
1994
Effects of a Novel Cardiotonic Agent (±)-6-[3-(3,4‐Dimethoxybenzylamino)-2‐Hydroxypropoxy]-2(1H)-Quinolinone (OPC‐18790) on Contractile Force, Cyclic AMP Level, and Aequorin Light Transients in Dog…
Summary: We studied the effects of a novel cardiotonic agent OPC-18790 [(±)-6-[3-(3,4-dimethoxybenzylamino)-2-hydroxypropoxy]-2… 
Review
1994
Review
1994
Nonglycoside inotropes in congestive heart failure. Are they beneficial or harmful?
1993
1993
Ca2+(-)dependent and Ca2+(-)independent vasorelaxation induced by cardiotonic phosphodiesterase inhibitors.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)