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C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia
Results indicate that Mincle is the first specific receptor for Malassezia species to be reported and plays a crucial role in immune responses to this fungus. Expand
The complete genomic sequence of Nocardia farcinica IFM 10152.
The genomic sequence of Nocardia farcinica IFM 10152, a clinical isolate, and the molecular basis of its versatility are determined, suggesting that gene duplications have resulted in a bacterium that can survive not only in soil environments but also in animal tissues, resulting in disease. Expand
Phylogeography of the fungal pathogen Histoplasma capsulatum
Combining DNA substitution rates of protein‐coding genes with the phylogeny suggests that the radiation of Histoplasma started between 3 and 13 million years ago in Latin America. Expand
Development of a Highly Efficient Gene Targeting System Induced by Transient Repression of YKU80 Expression in Candida glabrata
A new system whereby the expression of YKU80 was restored following a transient knockdown of expression during transformation, and the levels of mRNA transcription were restored and no difference in the survival ratio in vivo compared to that with the YK U80 wild-type strain was identified. Expand
The internal transcribed spacers and 5.8S rRNA gene show extensive diversity among isolates of the Cryptococcus neoformans species complex.
ITS sequencing is a useful technique for genotyping the three C. neoformans varieties and for subtyping within C. gattii. Expand
Molecular Characterization of New Clinical Isolates ofCandida albicans and C. dubliniensis in Japan: Analysis Reveals a New Genotype of C. albicans with Group I Intron
  • Miki Tamura, Kayo Watanabe, Y. Mikami, K. Yazawa, Kazuko Nishimura
  • Biology, Medicine
  • Journal of Clinical Microbiology
  • 1 December 2001
Genetic diversity in the five isolates of C. dubliniensis examined in the present study showed genetic diversity when they were compared by randomly amplified polymorphic DNA fingerprinting pattern analysis, and this diversity was also confirmed by the analysis of ITS region sequences. Expand
Construction of a pair of practical Nocardia-Escherichia coli shuttle vectors.
This work constructed a pair of Nocardia-Escherichia coli shuttle vectors, pNV18 and pNV19, by combining the mycobacterial plasmid pAL5000 with the E. coli vector pK18 or pK19, which are the first cloning vectors for practical use in N Cardia spp. Expand
Nocardia cyriacigeorgica is a significant pathogen responsible for nocardiosis in Japan and Thailand
It is found that N. cyriacigeorgica is usually differentiated from other Nocardia species by utilization of glucose and gluconate, but can also be differentiated by a characteristic synergistic effect between imipenem (IPM) and tobramycin (TOB). Expand
Nocardial Infections in Japan from 1992 to 2001, Including the First Report of Infection by Nocardia transvalensis
The most common factor that predisposed individuals to nocardial infection in Japan was therapy by immunosuppressive agents, followed by cancer, diabetes, diabetes and AIDS, which occurred more commonly in the elderly. Expand
Phagocytosis of Candida albicans by rabbit alveolar macrophages and guinea pig neutrophils.
Studies of host-parasite relationships at the cellular level, using Candida albicans and rabbit alveolar macrophages or guinea pig neutrophils are presented, showing no significant improvement of candidacidal activity was observed with macrophage from normal and immunized rabbits in immune serum. Expand