tumor necrosis factor binding

Known as: tumor necrosis factor 
Interacting selectively and non-covalently with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages. [GOC:jl… (More)
National Institutes of Health

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Recombinant Tumor Necrosis Factor Family ProteinRecombinant Tumor Necrosis Factor-AlphaTNF geneTNF protein, human
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Papers overview

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Highly Cited
2009
Highly Cited
2009
Regulation of drug transporter expression in human hepatocytes exposed to the proinflammatory cytokines tumor necrosis factor-alpha or interleukin-6.
Tumor necrosis factor (TNF)-alpha and interleukin (IL)-6 are proinflammatory cytokines known to alter expression of drug… (More)
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Highly Cited
2008
Highly Cited
2008
Tumor necrosis factor blockers influence macrophage responses to Mycobacterium tuberculosis.
Tumor necrosis factor (TNF)-alpha is a proinflammatory cytokine that mediates inflammation in response to various pathogens… (More)
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Highly Cited
2006
Highly Cited
2006
Tristetraprolin (TTP)-14-3-3 complex formation protects TTP from dephosphorylation by protein phosphatase 2a and stabilizes tumor necrosis factor-alpha mRNA.
Tumor necrosis factor (TNF)-alpha is a major cytokine produced by alveolar macrophages in response to pathogen-associated… (More)
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Highly Cited
2006
Highly Cited
2006
Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts.
Tumor necrosis factor (TNF) plays an important role in the pathogenesis of inflammatory bone loss through stimulation of… (More)
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Highly Cited
2005
Highly Cited
2005
Identification of direct genomic targets downstream of the nuclear factor-kappaB transcription factor mediating tumor necrosis factor signaling.
Tumor necrosis factor (TNF) is a pro-inflammatory cytokine that controls expression of inflammatory genetic networks. Although… (More)
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Highly Cited
2000
Highly Cited
2000
Physical and functional interaction of filamin (actin-binding protein-280) and tumor necrosis factor receptor-associated factor 2.
Tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) is an intracellular protein involved in signal transduction from… (More)
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Highly Cited
1990
Highly Cited
1990
Detection and localization of tumor necrosis factor in human atheroma.
Tumor necrosis factor (TNF) is a secretory product of normal macrophages that can cause cell necrosis, new blood vessel formation… (More)
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Highly Cited
1990
Highly Cited
1990
Elevation of tumor necrosis factor in head injury
Tumor necrosis factor (TNF) is a cytokine which mediates protein wasting in pathological states by promoting the catabolism of… (More)
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Highly Cited
1989
Highly Cited
1989
Isolation and characterization of a tumor necrosis factor binding protein from urine.
Tumor necrosis factor (TNF)/cachectin can produce both beneficial and harmful manifestations. Mechanisms may operate to… (More)
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1988
1988
A tumor necrosis factor binding protein is present in human biological fluids.
Tumor necrosis factor (TNF) possesses both beneficial and toxic bioactivities. Mechanisms may operate to counteract harmful… (More)
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