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TNF gene

Known as: TUMOR NECROSIS FACTOR, ALPHA, DIF, Tumor Necrosis Factor (TNF Superfamily, Member 2) Gene 
This gene is involved in apoptosis, cell growth and cell proliferation. It also plays a role in immune and inflammatory responses.
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Endotoxins and exotoxins are among the most potent bacterial inducers of cytokines. During infectious processes, the production… Expand
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Highly Cited
2003
Highly Cited
2003
Despite significant advances in intensive care therapy and antibiotics, severe sepsis accounts for 9% of all deaths in the United… Expand
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Highly Cited
2000
Highly Cited
2000
Here, we demonstrate a previously unknown function for the 70-kDa heat-shock protein (HSP70) as a cytokine. HSP70 bound with high… Expand
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Highly Cited
2000
Highly Cited
2000
The use of peptide–human histocompatibility leukocyte antigen (HLA) class I tetrameric complexes to identify antigen-specific CD8… Expand
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Highly Cited
1999
Highly Cited
1999
Members of the tumor necrosis factor (TNF) family induce pleiotropic biological responses, including cell growth, differentiation… Expand
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Highly Cited
1999
Highly Cited
1999
Bone resorption and remodeling is an intricately controlled, physiological process that requires the function of osteoclasts. The… Expand
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Highly Cited
1996
Highly Cited
1996
The death domain of tumor necrosis factor (TNF) receptor-1 (TNFR1) triggers distinct signaling pathways leading to apoptosis and… Expand
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Highly Cited
1991
Highly Cited
1991
Since a dysregulated synthesis of tumor necrosis factor alpha (TNF- alpha) may be involved in the pathogenesis of autoimmune… Expand
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Review
1989
Review
1989
Publisher Summary Interleukin-1 (IL-1) and tumor necrosis factor (TNF) participate in self-augmentation induction mechanisms… Expand
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Highly Cited
1986
Highly Cited
1986
We have used the quantitative binding of murine monoclonal antibodies to the surface of cultured human umbilical vein endothelial… Expand
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