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tryptanthrine

Known as: 6,12-dihydro-6,12-dioxoindole(2,1-b)quinazoline, tryptanthrin 
 
National Institutes of Health

Papers overview

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2013
2013
The natural product tryptanthrin (1a) represents a potential lead for new tuberculosis (TB) drugs since tryptanthrin and its… Expand
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Highly Cited
2013
Highly Cited
2013
Indoleamine 2,3-dioxygenase (IDO-1) is emerging as an important new therapeutic target for the treatment of cancer, neurological… Expand
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Highly Cited
2008
Highly Cited
2008
Bioassay-guided chromatographic separation of the cytotoxic MeOH extract of Phaius mishmensis led to the isolation of two known… Expand
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Highly Cited
2007
Highly Cited
2007
Alkyl, aryl, heteroaryl and acyl radicals have been cyclised onto the 2-position of 3H-quinazolin-4-one. The side chains… Expand
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Highly Cited
2002
Highly Cited
2002
Several indolo[2,1-b]quinazoline-6,12-dione (tryptanthrin) derivatives exhibited remarkable activity at concentrations below 100… Expand
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Highly Cited
2001
Highly Cited
2001
Tryptanthrin, a bioactive ingredient of Polygonum tinctorium Lour., is a member of the Indigo plant family and has potent… Expand
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Highly Cited
2001
Highly Cited
2001
Various extracts prepared from the traditional dye and medicinal plant Isatis tinctoria L. were submitted to a broad in vitro… Expand
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Highly Cited
2001
Highly Cited
2001
Abstract: We evaluated the effect of tryptanthrin and kaempferol, both isolated from Polygonum tinctorium Lour., against… Expand
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Highly Cited
2000
Highly Cited
2000
Nitric oxide (NO) and prostaglandins have been implicated in the pathogenesis of several inflammatory diseases. In this study, we… Expand
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Highly Cited
1979
Highly Cited
1979
From the leaves of Strobilanthes cusia, a folk remedy for athlete's foot in Okinawa, tryptanthrin was isolated as a strong… Expand
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