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Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis
Findings supporting the free radical hypothesis in skin carcinogenesis provide a promising rationale for the development of powerful new antioxidant strategies in the prevention and therapy of skin cancer. Expand
Characteristics of the Aging Skin.
A deeper understanding of the physiological basis of skin aging will facilitate progress in the treatment of the unwelcome sequelae of aging skin, both cosmetic and pathogenic. Expand
Intrinsic and extrinsic factors in skin ageing: a review
Better understanding of both the intrinsic and extrinsic influences on the ageing of the skin, as well as distinguishing the retractable aspects of cutaneous ageing from the irretractable, is crucial to this endeavour. Expand
Oxidative stress in malignant melanoma and non‐melanoma skin cancer
A growing body of evidence indicates that oxidative stress is involved in photocarcinogenesis, and reactive oxygen species participate in a number of pathophysiological processes including DNA damage and lipid peroxidation and are considered to be a key factor in tumour progression. Expand
Efficacy and safety of oral alitretinoin (9‐cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double‐blind,
Background  Patients with severe chronic hand eczema (CHE) refractory to topical corticosteroids currently have limited treatment options suited for chronic use, and few controlled clinical studiesExpand
The European standard series in 9 European countries, 2002/2003 – First results of the European Surveillance System on Contact Allergies
Since January 2001, the European Surveillance System on Contact Allergies (ESSCA), supported by European Union funding (contract QLK4‐CT‐2001‐00343), has started to collect patch‐test data. ThisExpand
Guidelines for diagnosis, prevention and treatment of hand eczema
Topical corticosteroids are recommended as first line treatment in the management of HE, however continuous long‐term treatment beyond six weeks only when necessary and under careful medical supervision is recommended. Expand
Photoaging is associated with protein oxidation in human skin in vivo.
The correlation between photodamage and protein oxidation was demonstrated for the first time, which hence may be a relevant pathophysiologic factor in photoaging. Expand
Frictional properties of human forearm and vulvar skin: influence of age and correlation with transepidermal water loss and capacitance.
The dynamic friction coefficient between skin and a Teflon probe and its correlation with age, body weight, height, transepidermal water loss and skin capacitance was studied in vulvar and forearm skin of 44 healthy female volunteers and it was concluded that the high friction coefficient of vulvar skin may be due to the increased hydration of vul var skin. Expand
Flagellate Dermatitis as a Bleomycin-Specific Adverse Effect of Cytostatic Therapy
An overview of all reported histologic changes in bleomycin-induced flagellate dermatitis, including an overview of the clinical and histologic features, is provided. Expand