Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

trypanothione synthetase

Known as: trypanothione synthase 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Trypanothione is a unique and essential redox metabolite of trypanosomatid parasites, the biosynthetic pathway of which is… Expand
Is this relevant?
2012
2012
A kinetic model of trypanothione [T(SH)(2)] metabolism in Trypanosoma cruzi was constructed based on enzyme kinetic parameters… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 2
  • figure 4
Is this relevant?
Review
2010
Review
2010
Polyamines (PAs) are essential metabolites in eukaryotes, participating in a variety of proliferative processes, and in… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2009
2009
The most promising targets for Leishmania-specific drug design are two key enzymes involved in the unique thiol-based metabolism… Expand
Is this relevant?
2008
2008
The bifunctional trypanothione synthetase-amidase catalyzes biosynthesis and hydrolysis of the glutathione-spermidine adduct… Expand
Is this relevant?
2005
2005
Trypanothione plays a pivotal role in defence against chemical and oxidant stress, thiol redox homoeostasis, ribonucleotide… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
2005
2005
In Crithidia fasciculata the biosynthesis of trypanothione (N(1),N(8)-bis(glutathionyl)spermidine; reduced trypanothione), a… Expand
Is this relevant?
2004
2004
In trypanosomes, the parasite-specific thiol trypanothione [T(SH)2] fulfills various functions, the best established being… Expand
Is this relevant?
2003
2003
Trypanothione [N(1),N(8)-bis(glutathionyl)spermidine] plays a central role in defence against oxidant damage, ribonucleotide… Expand
Is this relevant?
2003
2003
Abstract Trypanothione [T(SH)2], the major redox mediator in pathogenic trypanosomatids, is synthetized stepwise by two distinct… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?