trypanothione reductase

 
National Institutes of Health

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2010
2010
Visceral leishmaniasis, most lethal form of Leishmaniasis, is caused by Leishmania infantum in the Old world. Current… (More)
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2009
2009
There is an urgent need for new drugs for the treatment of tropical parasitic diseases such as human African trypanosomiasis… (More)
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2006
2006
The natural lignans veraguensin and grandisin have been reported to be active against Trypanosoma cruzi bloodstream forms. Aiming… (More)
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Highly Cited
2000
Highly Cited
2000
In Kinetoplastida, trypanothione and trypanothione reductase (TRYR) provide an intracellular reducing environment, substituting… (More)
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1999
1999
BACKGROUND Trypanothione reductase (TR) helps to maintain an intracellular reducing environment in trypanosomatids, a group of… (More)
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1999
1999
Lipoamide dehydrogenase (LipDH), trypanothione reductase (TR), and glutathione reductase (GR) catalyze the NAD(P)H-dependent… (More)
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1998
1998
Trypanothione reductase (TR), a flavoprotein oxidoreductase central to the unique thiol-redox system that operates in… (More)
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Highly Cited
1997
Highly Cited
1997
Parasitic protozoa belonging to the order Kinetoplastida contain trypanothione as their major thiol. Trypanothione reductase (TR… (More)
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1997
1997
A prediction algorithm of the binding affinity of ligands to trypanothione reductase (TR), the enzyme replacing glutathione… (More)
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1996
1996
Trypanothione reductase (TR) is an NADPH-dependent flavoprotein unique to protozoan parasites from the genera Trypanosoma and… (More)
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