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Interactions with aromatic rings in chemical and biological recognition.
This review focuses mainly on examples with biological relevance since one of its aims it to enhance the knowledge of molecular recognition forces that is essential for drug development. Expand
Metal-catalyzed cross-coupling reactions
Preface.List of Contributors.1 Mechanistic Aspects of Metal-Catalyzed C,C- and C,X-Bond-Forming Reactions (Antonio M. Echavarren and Diego J. Cardenas).1.1 Mechanisms of Cross-Coupling Reactions.1.2Expand
All-optical high-speed signal processing with silicon–organic hybrid slot waveguides
Integrated optical circuits based on silicon-on-insulator technology are likely to become the mainstay of the photonics industry. Over recent years an impressive range of silicon-on-insulator devicesExpand
Fluorine in Pharmaceuticals: Looking Beyond Intuition
Experimental progress in exploration of the specific influence of carbon-fluorine single bonds on docking interactions is reviewed and complementary analysis based on comprehensive searches in the Cambridge Structural Database and the Protein Data Bank is added. Expand
Systematic investigation of halogen bonding in protein-ligand interactions.
During the course of this research, an indication of an XB contact was obtained between a 4-chlorophenyl moiety of a ligand, whose binding affinity was enhanced by a factor of 13 compared to the unsubstituted phenyl derivative, and the backbone C=O group of Gly61 in the S3 pocket (Figure 1). Expand
Phosphate recognition in structural biology.
It is demonstrated that structure-based lead development and optimization should carefully address the phosphate-binding-site environment and also proposes new alternatives for filling such sites. Expand
Determination of End-to-End Distances in a Series of TEMPO Diradicals of up to 2.8 nm Length with a New Four-Pulse Double Electron Electron Resonance Experiment.
A four-pulse version of the pulsed double electron electron resonance (DEER) experiment has been applied to a series of TEMPO diradicals with well-defined interradical distances ranging from 1.4 to 2.8 nm, allowing broad distributions of electron-electron distances to be measured without dead-time artifacts. Expand
Modern Supramolecular Chemistry: Strategies for Macrocycle Synthesis
Cyclophanes Resorcinarene and calixarene synthesis Supramolecular Metallomacrocycles Supramolecular macrocycle synthesis by H-bonding assembly Supramolecular macrocycle synthesis by metal ionExpand
Silicon Organic Hybrid Technology—A Platform for Practical Nonlinear Optics
A cost-effective route to build electrically as well as optically controlled modulators in silicon photonics is reviewed, and two key devices in communications are exemplarily regarded in more detail. Expand