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trioxifene

Known as: (3,4-Dihydro-2-(4-methoxyphenyl)-1-naphthalenyl)(4-(2-(1-pyrrolidinyl)ethoxy)phenyl) Methanone, 3,4-dihydro-2-(p-methoxyphenyl)-1-naphthyl p-(2-(1-pyrrolidinyl)ethoxy)phenylketone, Methanone, (3,4-dihydro-2-(4-methoxyphenyl)-1naphthalenyl)(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)- 
A nonsteroidal selective estrogen receptor modulator (SERM) with potential antineoplastic activity. Trioxifene competes with estradiol in binding to… 
National Institutes of Health

Related topics

Related topics

4 relations
Lilly 133314NCIt Antineoplastic Agent Terminology

Broader (1)

Pyrrolidines

Narrower (1)

trioxifene mesylate

Papers overview

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Highly Cited
2014
Highly Cited
2014
Cannabinoid 1 and Transient Receptor Potential Vanilloid 1 Receptors Discretely Modulate Evoked Glutamate Separately from Spontaneous Glutamate Transmission
Action potentials trigger synaptic terminals to synchronously release vesicles, but some vesicles release spontaneously. G… 
2012
2012
Apparent Inverse Relationship between Cannabinoid Agonist Efficacy and Tolerance/Cross-Tolerance Produced by Δ9-Tetrahydrocannabinol Treatment in Rhesus Monkeys
Synthetic cannabinoids (CBs) [naphthalen-1-yl-(1-pentylindol-3-yl) methanone (JWH-018) and naphthalen-1-yl-(1-butylindol-3-yl… 
Highly Cited
2011
Highly Cited
2011
Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases
K2, a synthetic cannabinoid (SC), is an emerging drug of abuse touted as “legal marijuana” and marketed to young teens and first… 
2009
2009
Synthesis and Antimicrobial Activity of Dinaphtho(2,1-b)furan-2-yl-methanone and Their Oxime Derivatives
The reaction of 2-hydroxy-1-naphthaldehyde with 1,3-dichloroacetone and potassium carbonate was used to prepare dinaphtho[2,1-b… 
2003
2003
Allosteric enhancers of A1 adenosine receptors increase receptor-G protein coupling and counteract Guanine nucleotide effects on agonist binding.
Endogenous ligands of G protein-coupled receptors bind to orthosteric sites that are topologically distinct from allosteric sites… 
2002
2002
The 5-HT(1A) receptor agonist F 13640 attenuates mechanical allodynia in a rat model of trigeminal neuropathic pain.
Highly Cited
2001
Highly Cited
2001
5-HT1A receptor activation and antidepressant-like effects: F 13714 has high efficacy and marked antidepressant potential.
1998
1998
The effects of the novel benzodiazepine receptor inverse agonist Ru 34000 on ethanol-maintained behaviors.
1987
1987
Additive growth-inhibitory effects of DL-alpha-difluoromethylornithine and antiestrogens on MCF-7 breast cancer cell line.
1981
1981
Differential interaction of antiestrogens with cytosol estrogen receptors
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