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trilostane

Known as: (4Alpha,5alpha,17beta)-4,5-epoxy-3,17-dihydroxyandrost-2-ene-2-carbonitrile, Trilostano, trilostane [Chemical/Ingredient] 
A synthetic derivative of androstane with adrenocortical suppressive properties. Trilostane reversibly inhibits 3 beta-hydroxysteroid dehydrogenase… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (4)

Abortifacient Agents, SteroidalAntineoplastic AgentsDihydrotestosteroneEnzyme Inhibitors
analogs & derivativestrilostane 120 MG Oral Capsule [Vetoryl]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Urinary corticoid: creatinine ratios in dogs with pituitary-dependent hypercortisolism during trilostane treatment.
BACKGROUND The adrenocorticotropic hormone (ACTH) stimulation test is used to evaluate trilostane treatment in dogs with… 
Review
2006
Review
2006
Update on drugs used to treat endocrine diseases in small animals.
2004
2004
DHEA and DHEA sulfate differentially regulate neural androgen receptor and its transcriptional activity.
2003
2003
Use of trilostane for the treatment of pituitary-dependent hyperadrenocorticism in a cat.
Hyperadrenocorticism occurs much less frequently in cats than in dogs and, at present, is more difficult to manage successfully… 
2003
2003
Steroids Modulate N-Methyl-D-aspartate-Stimulated [3H]Dopamine Release from Rat Striatum via σ Receptors
Steroids have been proposed as endogenous ligands at σ receptors. In the current study, we examined the ability of steroids to… 
Highly Cited
1989
Highly Cited
1989
Steroid synthesis in rat brain cell cultures.
1989
1989
Neurosteroids: steroidogenesis in primary cultures of rat glial cells after release of aminoglutethimide blockade.
1984
1984
Progesterone production by human fetal membranes: an in vitro incubation system for studying hormone production and metabolism.
1983
1983
INHIBITION OF 3‐BETA‐HYDROXY STEROID DEHYDROGENASE ACTIVITY IN FIRST TRIMESTER HUMAN PREGNANCY WITH TRILOSTANE AND WIN 32729
The effects of equivalent doses of two inhibitors of the 3‐beta‐hydroxy steroid dehydrogenase enzyme system—WIN 24540 (trilostane… 
1978
1978
Angiotensin stimulates both early and late steps in aldosterone biosynthesis in isolated bovine glomerulosa cells.
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