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Dihydrotestosterone

Known as: (5alpha,17beta)-17-Hydroxyandrostan-3-one, 5alpha-Dihydrotestosterone, 5 alpha DHT 
The most potent androgen, required for sex development. Dihydrotestosterone is synthesized from testosterone in the prostate gland, testes, hair… 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
In the majority of cases, advanced prostate cancer responds initially to androgen deprivation therapy by depletion of gonadal… 
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Highly Cited
2005
Highly Cited
2005
Purpose: Prostate cancer eventually recurs during androgen deprivation therapy despite castrate levels of serum androgens… 
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Review
2004
Review
2004
  • R. Auchus
  • Trends in Endocrinology & Metabolism
  • 2004
  • Corpus ID: 10631647
Dihydrotestosterone (DHT) is the androgen responsible for formation of the male external genitalia during embryogenesis and for… 
Highly Cited
2004
Highly Cited
2004
Dihydrotestosterone (DHT) is the primary metabolite of testosterone in the prostate and skin. Testosterone is converted to DHT by… 
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Androgens are involved in the development of prostate cancer. Finasteride, an inhibitor of 5alpha-reductase, inhibits… 
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Highly Cited
2003
Highly Cited
2003
This article examines the role of the androgen dihydrotestosterone (DHT) in the healthy and diseased prostate and considers the… 
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Highly Cited
1990
Highly Cited
1990
Testosterone and dihydrotestosterone are believed to exert their androgenic effects by interacting with a single intracellular… 
Review
1987
Review
1987
Though unnecessary for life itself, androgens are essential for the propagation of the species and for establishment and… 
Highly Cited
1983
Highly Cited
1983
The LNCaP cell line was established from a metastatic lesion of human prostatic adenocarcinoma. The LNCaP cells grow readily in… 
Highly Cited
1974
Highly Cited
1974
Abstract Two 46 XY siblings with familial incomplete male pseudohermaphroditism, Type 2, inherited as an apparent autosomal…