Dihydrotestosterone

Known as: (5alpha,17beta)-17-Hydroxyandrostan-3-one, 5alpha-Dihydrotestosterone, 5 alpha DHT 
The most potent androgen, required for sex development. Dihydrotestosterone is synthesized from testosterone in the prostate gland, testes, hair… (More)

Topic mentions per year

Topic mentions per year

1950-2017
010020030019502016

Papers overview

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Highly Cited
2011
Highly Cited
2011
In the majority of cases, advanced prostate cancer responds initially to androgen deprivation therapy by depletion of gonadal… (More)
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Highly Cited
2008
Highly Cited
2008
Although systemic androgen deprivation prolongs life in advanced prostate cancer, remissions are temporary because patients… (More)
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Highly Cited
2006
Highly Cited
2006
Androgen receptor (AR) plays a central role in prostate cancer, and most patients respond to androgen deprivation therapies, but… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE Prostate cancer eventually recurs during androgen deprivation therapy despite castrate levels of serum androgens… (More)
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Highly Cited
2004
Highly Cited
2004
Dihydrotestosterone (DHT) is the primary metabolite of testosterone in the prostate and skin. Testosterone is converted to DHT by… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE Prostate cancer that recurs during androgen deprivation therapy is referred to as androgen-independent. High levels of… (More)
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Highly Cited
2003
Highly Cited
2003
This paper addresses the problem of churn—the continuous process of node arrival and departure—in distributed hash tables (DHTs… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Androgens are involved in the development of prostate cancer. Finasteride, an inhibitor of 5alpha-reductase, inhibits… (More)
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Highly Cited
2002
Highly Cited
2002
We used longitudinal data from the Massachusetts Male Aging Study, a large population-based random-sample cohort of men aged 40… (More)
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Highly Cited
1983
Highly Cited
1983
The LNCaP cell line was established from a metastatic lesion of human prostatic adenocarcinoma. The LNCaP cells grow readily in… (More)
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