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tifluadom

Known as: 1-methyl-2-(3-thienylcarbonyl)aminomethyl-5-(2-fluorophenyl)-H-2,3-dihydro-1,4-benzodiazepine, 3-Thiophenecarboxamide, N-((5-(2-fluorophenyl)-2,3-dihydro-1-methyl-1H-1,4-benzodiazepin-2-yl)methyl)-, titfluadom 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

BenzodiazepinesDiuretics

Narrower (3)

KC 5103KC 5911KC 6128

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1989
1989
Effects of different opiates on hypothalamic monoamine turnover and on plasma LH levels in pro-oestrous rats
Highly Cited
1988
Highly Cited
1988
Effect of kappa-opioid receptor agonists on morphine analgesia in morphine-naive and morphine-tolerant rats.
1988
1988
Opposite effects of κ-opioid agonists on gastric emptying of liquids and solids in dogs
1987
1987
Involvement of opiate receptor subtypes in the modulation of LHRH secretion by the cockerel (Gallus domesticus) mediobasal hypothalamus in vitro.
Using an in-vitro superfusion system, the relative importance of three distinct subtypes of the opiate receptor in the control of… 
1986
1986
The benzodiazepine (+)-tifluadom (KC-6128), but not its optical isomer (KC-5911) induces opioid kappa receptor-related EEG power spectra and evoked potential changes.
Tifluadom, a benzodiazepine with purported opioid receptor-related analgesic properties, was studied in regard to its acute… 
1985
1985
Effects of kappa opiate agonists on palatable food consumption in non-deprived rats, with and without food preloads
1985
1985
Effects of opiates on urine output in the water-loaded rat and reversal by β-funaltrexamine
1984
1984
Kappa-opioid diuretic effects of tifluadom, a benzodiazepine opioid agonist.
Tifluadom produced a dose-related (0.08-5 mg kg-1) diuresis in normally hydrated rats. This diuretic effect was antagonized by… 
1984
1984
The role of opioid receptor sub‐types in tifluadom‐induced feeding
There is now considerable evidence that opioid agonists and benzodiazepines increase food and water intake in a variety of animal… 
Highly Cited
1982
Highly Cited
1982
Unexpected opioid activity in a known class of drug.
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