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Trends in reproductive performance in Southeastern Holstein and Jersey DHI herds.
Trends in average days open and services per conception from 1976 to 1999 were examined in 532 Holstein and 29 Jersey herds from 10 Southeastern states. Three-year averages for eight intervals (time)Expand
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Physiological pathways regulating the activity of magnocellular neurosecretory cells
Magnocellular oxytocin and vasopressin cells are among the most extensively studied neurons in the brain; their large size and high synthetic capacity, their discrete, homogeneous distribution andExpand
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Phasic spike patterning in rat supraoptic neurones in vivo and in vitro
In vivo, most vasopressin cells of the hypothalamic supraoptic nucleus fire action potentials in a ‘phasic’ pattern when the systemic osmotic pressure is elevated, while most oxytocin cells fireExpand
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Autocrine feedback inhibition of plateau potentials terminates phasic bursts in magnocellular neurosecretory cells of the rat supraoptic nucleus
Phasic activity in magnocellular neurosecretory cells is characterized by alternating periods of activity (bursts) and silence. During phasic bursts, action potentials are superimposed on plateauExpand
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Physiological Regulation of Magnocellular Neurosecretory Cell Activity: Integration of Intrinsic, Local and Afferent Mechanisms
The hypothalamic supraoptic and paraventricular nuclei contain magnocellular neurosecretory cells (MNCs) that project to the posterior pituitary gland where they secrete either oxytocin orExpand
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κ-Opioid Regulation of Neuronal Activity in the Rat Supraoptic Nucleus In Vivo
We investigated the influence of endogenous κ-opioids on the activity of supraoptic neurons in vivo. Administration of the κ-antagonist nor-binaltorphimine (200 μg/kg, i.v.), increased the activityExpand
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Responses of Magnocellular Neurons to Osmotic Stimulation Involves Coactivation of Excitatory and Inhibitory Input: An Experimental and Theoretical Analysis
How does a neuron, challenged by an increase in synaptic input, display a response that is independent of the initial level of activity? Here we show that both oxytocin and vasopressin cells in theExpand
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Glial Regulation of Neuronal Function: From Synapse to Systems Physiology
Classically, glia have been regarded as non‐excitable cells that provide nourishment and physical scaffolding for neurones. However, it is now generally accepted that glia are active participants inExpand
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State‐dependent changes in astrocyte regulation of extrasynaptic NMDA receptor signalling in neurosecretory neurons
Non‐technical summary  Glutamate is a critical excitatory neurotransmitter in the modulation of hypothalamic neuronal activity and neurosecretion from the posterior pituitary. Still, the preciseExpand
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Phasic bursts in rat magnocellular neurosecretory cells are not intrinsically regenerative in vivo
Vasopressinergic hypothalamic magnocellular neurosecretory cells fire in phasic bursts. Burst initiation involves summation of postsynaptic potentials to generate action potentials. Action potentialsExpand
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