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thymidine glycol

Known as: 5,6-dihydro-5,6-dihydroxythymidine, 5,6-dihydroxy-5,6-dihydrothymidine, glycolthymidine 
National Institutes of Health

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Broader (1)

Thymidine
analogs & derivatives

Papers overview

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2006
2006
Photoinduced reductive repair of thymine glycol: implications for excess electron transfer through DNA containing modified bases.
Photoinduced reduction of thymine glycol in oligodeoxynucleotides was investigated using either a reduced form of flavin adenine… 
Review
1998
Review
1998
Estimation of oxidative DNA damage in man from urinary excretion of repair products.
DNA is constantly damaged and repaired in living cells. The repair products of the oxidative DNA lesions, i.e. oxidised… 
1998
1998
Detection of thymine [2+2] photodimer repair in DNA: selective reaction of KMnO4.
The specific reaction of potassium permanganate with thymine in single-stranded DNA was employed to analyze thymine [2+2] dimer… 
Highly Cited
1993
Highly Cited
1993
Characterization of the effects of a thymine glycol residue on the structure, dynamics, and stability of duplex DNA by NMR.
1993
1993
Oxidative damage to DNA: levels of thymine glycol and thymidine glycol in neoplastic human urines.
We have measured the levels of thymine glycol (TG) and thymidine glycol (dTG) in human urine, using an HPLC method. The results… 
Highly Cited
1993
Highly Cited
1993
Sensitivity to tumor promotion of SENCAR and C57BL/6J mice correlates with oxidative events and DNA damage.
Significant differences in sensitivity to multistage carcinogenesis have been noted between mice that are sensitive (SENCAR) and… 
1992
1992
Reversed-phase high-performance liquid chromatography-thermospray mass spectrometry of radiation-induced decomposition products of thymine and thymidine.
1988
1988
Dihydrothymidine and thymidine glycol triphosphates as substrates for DNA polymerases: differential recognition of thymine C5-C6 bond saturation and sequence specificity of incorporation.
The ability of dihydrothymidine (DHdTTP) and thymidine glycol (dTTP-GLY) 5'-triphosphates to serve as substrates for different… 
Highly Cited
1981
Highly Cited
1981
Identification of the cis-thymine glycol moiety in chemically oxidized and gamma-irradiated deoxyribonucleic acid by high-pressure liquid chromatography analysis.
5,6-Dihydroxy-5,6-dihydrothymine (thymine glycol) is formed in DNA by chemical oxidants and ionizing radiation. We describe the… 
1971
1971
The permanganate oxidation of thymidine and thymidylic acid.
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